专利检索 ap:("Oregon Health & Science University" OR "The United States Government Represented by the Department of Veterans Affairs") AND inv:"LEWINSOHN, David M." 第 1 页

1.

发明授权
METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION 有权

公开(公告)号：EP3360566B1

公开(公告)日：2019-12-25

申请号：EP18162110.3

申请日：2010-11-19

申请人： Oregon Health & Science University , The United States Government Represented by the Department of Veterans Affairs

发明人： LEWINSOHN, David M. , LEWINSOHN, Deborah A.

IPC分类号： A61K38/16 , A61K39/39 , C12N15/867 , C12N15/86 , A61P31/06 , A61K39/04 , A61K38/00 , A61K39/385 , A61K49/00 , G01N33/569 , A61K39/00 , A61K9/00

2.

发明公开
METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION 审中-公开

公开(公告)号：EP3360566A1

公开(公告)日：2018-08-15

申请号：EP18162110.3

申请日：2010-11-19

申请人： Oregon Health & Science University , The United States Government Represented by the Department of Veterans Affairs

发明人： LEWINSOHN, David M. , LEWINSOHN, Deborah A.

IPC分类号： A61K38/16 , A61K39/39 , C12N15/867 , C12N15/86 , A61P31/06 , A61K39/04 , A61K38/00 , A61K39/385 , A61K49/00 , G01N33/569 , A61K39/00 , A61K9/00

摘要： Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8 + T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8 + T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.