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1.发明公开N-SUBSTITUTED AMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS 有权N-取代AS氨基萘满神经肽Y Y5受体配体和它们用于肥胖等疾病的治疗
公开(公告)号：EP1076644A1
公开(公告)日：2001-02-21
申请号：EP99918500.2
申请日：1999-04-12
发明人： DAX, Scott, L. , LOVENBERG, Timothy, Walter , MCNALLY, James, J. , REITZ, Allen, B. , YOUNGMAN, Mark, Andrew
IPC分类号： C07C311/15 , C07C311/20 , C07C311/21 , C07C311/37 , C07C311/25 , C07D333/34 , C07D213/38 , C07D233/54 , C07D307/52 , C07D333/20 , A61K31/18 , A61K31/44 , A61K31/34 , A61K31/38 , A61K31/415
CPC分类号： C07D233/64 , C07C311/18 , C07C311/29 , C07C311/37 , C07C317/14 , C07D213/38 , C07D307/52 , C07D333/20 , C07D333/34
摘要： β-Aminotetralin derivatives of formula (1): which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing a β-aminotetralins derivative as the active ingredient are described. The β-aminotetralins are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.
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2.发明授权N-SUBSTITUTED AMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS 有权N-取代AS氨基萘满神经肽Y Y5受体配体和它们用于肥胖等疾病的治疗
公开(公告)号：EP1076644B1
公开(公告)日：2004-06-23
申请号：EP99918500.2
申请日：1999-04-12
发明人： DAX, Scott, L. , LOVENBERG, Timothy, Walter , MCNALLY, James, J. , REITZ, Allen, B. , YOUNGMAN, Mark, Andrew
IPC分类号： C07C311/15 , C07C311/20 , C07C311/21 , C07C311/37 , C07C311/25 , C07D333/34 , C07D213/38 , C07D233/54 , C07D307/52 , C07D333/20 , A61K31/18 , A61K31/44 , A61K31/34 , A61K31/38 , A61K31/415
CPC分类号： C07D233/64 , C07C311/18 , C07C311/29 , C07C311/37 , C07C317/14 , C07D213/38 , C07D307/52 , C07D333/20 , C07D333/34
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