OLIGOPEPTIDE IMPROVING DIFFERENTIATION OF OSTEOBLASTS
    1.
    发明公开
    OLIGOPEPTIDE IMPROVING DIFFERENTIATION OF OSTEOBLASTS 有权
    OLIGOPEPTID MIT OSTEOBLASTENDIFFERENZIERUNG

    公开(公告)号:EP2540739A1

    公开(公告)日:2013-01-02

    申请号:EP10846675.6

    申请日:2010-02-26

    IPC分类号: C07K14/51 C07K7/08 A61L27/54

    摘要: The present invention relates to oligopeptides applicable to a dental implant, which are selected from the group consisting of PEP7 (SEQ ID No. 1), PEP71 (SEQ ID No. 2), EP72 (SEQ ID No. 3), PEP73 (SEQ ID No. 4), PEP74 (SEQ ID No. 5), PEP75 (SEQ ID No. 6) and PEP76 (SEQ ID No. 7). The oligopeptides of the present invention have very high reactivity for a BMP-specific receptor to increase osteoblastic differentiation and calcification, thereby showing improved osteointegration and osteogenesis.

    摘要翻译: 本发明涉及适用于牙科植入物的寡肽,其选自PEP7(SEQ ID No.1),PEP71(SEQ ID No.2),PEP72(SEQ ID No.3),PEP73(SEQ ID No.4),PEP74(SEQ ID No.5),PEP75(SEQ ID No.6)和PEP76(SEQ ID No.7)。 本发明的寡肽对于BMP-特异性受体具有非常高的反应性以增加成骨细胞分化和钙化,从而显示改善的骨整合和成骨。