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公开(公告)号：EP1656942A2
公开(公告)日：2006-05-17
申请号：EP05025442.4
申请日：1998-08-04
发明人： Uchiyama, Shigeto , Ueno, Tomomi , Imaizumi, Kiyoko , Kumemura, Megumi , Masaki, Kyosuke , Shimizu, Seiichi
CPC分类号： C12R1/46 , A23C9/1236 , A23C9/1315 , A23C11/106 , A23L2/52 , A23L21/15 , A23L29/065 , A23L33/105 , A23L33/11 , A23L33/135 , A23L33/185 , A61K31/35 , A61K35/74 , A61K35/744 , A61K36/48 , C12P17/06 , C12R1/01 , A61K2300/00
摘要： The present invention relates to a composition comprising a daidzein-containing substance and a strain of microorganism capable of metabolizing daidzein to equol as essential ingredients.
摘要翻译： 本发明涉及包含含黄豆苷原的物质和能够将黄豆苷原代谢为雌马酚作为必需成分的微生物菌株的组合物。
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2.发明公开
公开(公告)号：EP3351258A1
公开(公告)日：2018-07-25
申请号：EP18160164.2
申请日：2006-12-05
发明人： Kimura, Hiroyuki , Yamauchi, Takeshi , Ueno, Tomomi , Suzuki, Toshimi , Tadano, Kentaro, , Sato, Ikutaro , Uchiyama, Shigeto , Oono, Masahiro , Mizuno, Masatoshi
IPC分类号： A61K35/74 , A61P13/08 , A61P15/12 , A61P19/10 , A61P3/00 , A61K8/97 , A61Q19/00 , A61K8/49 , A61Q19/02 , A61Q19/10 , A23L11/00 , A23L33/105
CPC分类号： A23L11/09 , A23L33/105 , A23V2002/00 , A61K8/498 , A61K8/97 , A61K2800/85 , A61Q19/00 , A61Q19/02 , A61Q19/10 , A23V2250/21172 , A23V2250/5488 , A23V2200/3262
摘要： An object of the invention is to provide an equol-containing fermented soybean hypocotyl material that is useful for foods, pharmaceutical preparations, cosmetic products, etc. The equol-containing fermented soybean hypocotyl material of the invention is obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.
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3.发明公开Equol-producing lactic acid bacteria-containing composition 有权Equolproduzierende，milchsäurebakterienhaltigeZusammensetzung
公开(公告)号：EP2548455A1
公开(公告)日：2013-01-23
申请号：EP12187419.2
申请日：2004-06-29
发明人： Uchiyama, Shigeto , Ueno, Tomomi , Suzuki, Toshimi
IPC分类号： A23L1/30 , A23L1/20 , C12N1/20 , C12P17/06 , A61K35/74 , A61P15/12 , A61P19/10 , A61P35/00 , A23C11/10 , A23C9/123
CPC分类号： A61K35/747 , A23C9/123 , A23C11/106 , A23L33/135 , A23Y2220/00 , A61K35/744 , C12P17/06 , C12R1/46
摘要： The present invention provides an equol-producing lactic acid bacteria-containing composition comprising, as an essential component thereof, a lactic acid bacterial strain belonging to the genus Lactococcus having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol.
Such a composition is effective for the prevention and alleviation of malaise inclusive of climacteric disturbance in middle-aged and elderly women for which no effective prophylactic method or alleviating means has heretofore been available.摘要翻译： 本发明提供含有雌马酚产生乳酸菌的组合物，其含有属于乳球菌属的乳酸菌菌株作为其主要成分，其具有使用至少一种黄豆苷元化合物，所述黄豆苷元化合物选自黄豆苷元苷 ，黄豆苷元和二氢黄豆苷元产生雌马酚。 这种组合物对于预防和缓解包括中年和老年妇女更年期障碍的不适，其中迄今尚无有效的预防方法或缓解方法是有效的。
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4.发明授权Equol-containing fermentation product of soybean embryonic axis, and method for production thereof 有权大豆胚轴的含有雌马酚的发酵产物及其生产方法
公开(公告)号：EP2474237B1
公开(公告)日：2018-04-25
申请号：EP12160323.7
申请日：2006-12-05
发明人： Kimura, Hiroyuki , Yamauchi, Takeshi , Ueno, Tomomi , Suzuki, Toshimi , Tadano, Kentaro , Sato, Ikutaro , Uchiyama, Shigeto , Oono, Masahiro , Mizuno, Masatoshi
CPC分类号： A23L11/09 , A23L33/105 , A23V2002/00 , A61K8/498 , A61K8/97 , A61K2800/85 , A61Q19/00 , A61Q19/02 , A61Q19/10 , A23V2250/21172 , A23V2250/5488 , A23V2200/3262
摘要： An object of the invention is to provide an equol-containing fermented soybean hypocotyl material that is useful for foods, pharmaceutical preparations, cosmetic products, etc. The equol-containing fermented soybean hypocotyl material of the invention is obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.
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5.发明公开
公开(公告)号：EP3563689A1
公开(公告)日：2019-11-06
申请号：EP19175944.8
申请日：2009-09-18
发明人： Isono, Yoshikazu , Mori, Hisako , Ueno, Tomomi , Endo, Rieko , Kumemura, Megumi , Abiru, Yasuhiro , Uchiyama, Shigeto
IPC分类号： A23C9/123 , A23C9/13 , A23C11/10 , A23L11/00 , A23L29/00 , A23L33/135 , C07D311/60
摘要： An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained.
When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.-
公开(公告)号：EP2548455B1
公开(公告)日：2016-08-31
申请号：EP12187419.2
申请日：2004-06-29
发明人： Uchiyama, Shigeto , Ueno, Tomomi , Suzuki, Toshimi
IPC分类号： A23L33/00 , A23L11/00 , A23C9/123 , A23C11/10 , C12N1/20 , C12P17/06 , A61K35/74 , A61P19/10 , A61P15/12
CPC分类号： A61K35/747 , A23C9/123 , A23C11/106 , A23L33/135 , A23Y2220/00 , A61K35/744 , C12P17/06 , C12R1/46
摘要： Made up of a step of preparing a map expressing a correlation between solid phase percentage and viscosity of a slurry-form semi-solid metal (27) for a given metal composition; a step of setting a target viscosity corresponding to a target solid phase percentage using this map; a viscosity measuring step of measuring the viscosity of a semi-solid metal in a vessel (13) while cooling it; and a step of carrying out cooling until this viscosity reaches the target viscosity, by these steps being carried out in from the preparation of the map expressing the correlation between solid phase percentage and viscosity of the semi-solid metal to the end of cooling of the semi-solid metal the solid phase percentage of the semi-solid metal is made to match the target solid phase percentage. Because the viscosity is detected, the affects of cooling rate changes and time can be eliminated, and it is possible to raise management accuracy of the solid phase percentage of the semi-solid metal much further than with related art management based on time.
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7.发明公开
公开(公告)号：EP2474237A1
公开(公告)日：2012-07-11
申请号：EP12160323.7
申请日：2006-12-05
发明人： Kimura, Hiroyuki , Yamauchi, Takeshi , Ueno, Tomomi , Suzuki, Toshimi , Tadano, Kentaro , Sato, Ikutaro , Uchiyama, Shigeto , Oono, Masahiro , Mizuno, Masatoshi
CPC分类号： A23L1/2008 , A23L11/09 , A23L33/105 , A23V2002/00 , A61K8/498 , A61K8/97 , A61K2800/85 , A61Q19/00 , A61Q19/02 , A61Q19/10 , A23V2250/21172 , A23V2250/5488 , A23V2200/3262
摘要： An object of the invention is to provide an equol-containing fermented soybean hypocotyl material that is useful for foods, pharmaceutical preparations, cosmetic products, etc. The equol-containing fermented soybean hypocotyl material of the invention is obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.
摘要翻译： 本发明的目的是提供可用于食品，药物制剂，化妆品等的含雌马酚的发酵大豆下胚轴材料。本发明的含雌马酚的发酵大豆下胚轴材料是通过使用至少发酵大豆胚轴 一种通过利用至少一种选自二酮糖苷，黄豆苷原和二氢黄豆苷元的黄豆苷元化合物具有雌马酚产生能力的微生物。
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公开(公告)号：EP1656942A3
公开(公告)日：2008-02-27
申请号：EP05025442.4
申请日：1998-08-04
发明人： Uchiyama, Shigeto , Ueno, Tomomi c/o Saga Laboratories of Otsuka Pharm , Imaizumi, Kiyoko c/o Tokushima Labor. of Otsuka Ph , Kumemura, Megumi , Masaki, Kyosuke , Shimizu, Seiichi
CPC分类号： C12R1/46 , A23C9/1236 , A23C9/1315 , A23C11/106 , A23L2/52 , A23L21/15 , A23L29/065 , A23L33/105 , A23L33/11 , A23L33/135 , A23L33/185 , A61K31/35 , A61K35/74 , A61K35/744 , A61K36/48 , C12P17/06 , C12R1/01 , A61K2300/00
摘要： The present invention relates to a composition comprising a daidzein-containing substance and a strain of microorganism capable of metabolizing daidzein to equol as essential ingredients.
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