公开(公告)号：EP1517877A1

公开(公告)日：2005-03-30

申请号：EP03739199.2

申请日：2003-06-19

申请人： PCBU Services, Inc.

发明人： ALLEN, David, Robert ,  ACHENBACH-MCCARTHY, Crystal

IPC分类号： C07B57/00 ,  C07C253/30 ,  C07C255/24

CPC分类号： C07C253/30 ,  C07B2200/07 ,  C07C255/24

摘要： A process and intermediates for producing 3-amino nitriles. The process involves resolving an enantiomeric mixture of chiral 3-amino nitriles in the presence of a chiral acid in a solvent system to produce a chiral 3-amino nitrile salt. The process may further comprise a recrystalizing step, wherein an enantiomerically enriched 3-amino nitrile salt is produced. The process may further comprise a salt exchanging step, wherein another acid is added to the chiral 3-amino nitrile salt or the enantiomerically enriched 3-amino nitrile salt to produce another 3- amino nitrile salt.