公开(公告)号：EP1373322A1

公开(公告)日：2004-01-02

申请号：EP02720698.6

申请日：2002-03-28

申请人： PHARMACIA DIAGNOSTICS AB

发明人： LAFFER, Sylvia ,  ROUX, Kenneth, H. ,  SPERR, Wolfgang, R. ,  VALENT, Peter ,  KRAFT, Dietrich ,  VALENTA, Rudolf ,  HÖGBOM, Erik ,  ADRIANSSON, Jonas ,  GRÖNLUND, Hans

IPC分类号： C07K16/42 ,  A61K39/395 ,  A61P37/00

CPC分类号： C07K16/16 ,  A61K2039/505 ,  C07K16/4291 ,  C07K2317/24 ,  C07K2317/52 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/76

摘要： The present invention relates to a novel drug candidate having a potential for universal therapy of allergy and asthma. The invention provides a Fab (antibody fragment), having the following characteristics: a) inhibits the IgE- FcεRI interaction; b) binds to free and cell-bound IgE; and c) is non-anaphylactic.