公开(公告)号：EP1181298B1

公开(公告)日：2006-07-19

申请号：EP00920937.0

申请日：2000-04-19

申请人： PLIVA-ISTRAZIVACKI INSTITUT d.o.o.

发明人： LAZAREVSKI, Gorjana ,  ALIHODZIC, Sulejman ,  KOBREHEL, Gabrijela ,  MUTAK, Stjepan

IPC分类号： C07H17/08 ,  A61K31/70

CPC分类号： C07H17/08

摘要： The invention relates to novel 15-membered 8a- and 9a-lactams from the class of 6-O-methyl-erythromycin A of general formula (I), their pharmaceutically acceptable addition salts with inorganic or organic acids and their hydrates, wherein A stands for NH group and B simultaneously stands for C=O group, or A stands for C=O group and B simultaneously stands for NH group, and the radicals R , R , R , R , R , R have the meaning given in claim 1.