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公开(公告)号:EP1873165B1
公开(公告)日:2012-06-06
申请号:EP06013165.3
申请日:2006-06-26
申请人: PLS-Design GmbH
IPC分类号: C07K14/435 , C12N9/50 , C12N15/09 , C12Q1/68 , G01N33/48
CPC分类号: C07K14/43572 , C12N9/6402
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公开(公告)号:EP1873165A1
公开(公告)日:2008-01-02
申请号:EP06013165.3
申请日:2006-06-26
申请人: PLS-Design GmbH
IPC分类号: C07K14/435 , C12N9/50 , C12N15/09 , C12Q1/68 , G01N33/48
CPC分类号: C07K14/43572 , C12N9/6402
摘要: The present invention relates to a nucleic acid encoding a polypeptide capable of binding to IgE from subjects allergic to venom of an insect from the order Hymenoptera having a homology of more than 70% to the amino acid sequence of SEQ ID NO: 2, which is the honey bee allergen C (Api m 5). The invention further relates to expression vectors, host cells and polypeptides encoded by the nucleic acid, as well as diagnostic and pharmaceutical uses thereof.
摘要翻译: 本发明涉及一种编码能够从与来自SEQ ID NO:2的氨基酸序列具有多于70%同源性的膜翅目昆虫的毒液过敏的受试者的能够结合IgE的多肽的核酸,其是SEQ ID NO: 蜂蜜过敏原C(Api m 5)。 本发明还涉及由核酸编码的表达载体,宿主细胞和多肽,以及其诊断和药物用途。
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