摘要:
Anticorps spécifiques aux épitopes spécifiques de CEA et aux épitopes d'antigènes trans-réactifs de CEA. Des procédés d'utilisation de ces anticorps et d'antigènes purifiés de CEA et d'antigènes trans-réactifs sont également décrits.
摘要:
Antibodies specific to specific CEA epitopes and epitopes of CEA-cross-reactive antigens. Methods of use of these antibodies and purified CEA antigens and cross-reactive antigens are also provided.
摘要:
A method for enhancing target specificity of antibody localization comprises injecting a second antibody specific to a labeled target-specific antibody to reduce the level of non-targeted circulating specific antibody, thereby increasing the localization ratio. The foregoing method is useful for imaging tumors and infectious lesions, and for therapy.
摘要:
A tryptic peptide is produced by partial tryptic digestion of purified, high molecular size colon-specific antigen-p (CSAp), to produce a lower molecular size antigen carrying the CSAp antigenic determinant. The tryptic peptide is used to produce monospecific anti-CSAp antibodies.
摘要:
Methods are provided for using radiolabeled antibodies and antibody fragments specific to tumor-associated markers for detection, localization and therapy of tumors. Mixtures of labeled antibodies and/or antibody fragments with varied specificity or multivalent hybrid fragments permit detection and localization of more than one tumor type. Antibodies, antibody fragments and injectable compositions for use in the methods of the invention are also provided.
摘要:
An improved method for lymphoscintigraphy or magnetic resonance lymphography involves subtraction of a negative image produced using a gross imaging agent from a positive image produced with a specific antibody imaging agent. Another embodiment of the invention uses an antibody to lymphatic tissue as an imaging agent for lymphatics. A further embodiment uses a magnetic resonance image enhancing agent for magnetic resonance lymphography. Reagents and kits for use in the foregoing method are also provided.
摘要:
A tryptic peptide is produced by partial tryptic digestion of purified, high molecular size colon-specific antigen-p (CSAp), to produce a lower molecular size antigen carrying the CSAp antigenic determinant. The tryptic peptide is used to produce monospecific anti-CSAp antibodies.