公开(公告)号：EP1623211A4

公开(公告)日：2006-10-25

申请号：EP04750558

申请日：2004-04-23

申请人： PROMETHEUS BIOSCIENCES INC

发明人： HEFTI JOHN J ,  DRAKO DEAN M

IPC分类号： G01N21/47 ,  B01J19/00 ,  B01L3/00 ,  B01L7/00 ,  G01D1/16 ,  G01N20060101 ,  G01N15/06 ,  G01N25/58 ,  G01N33/00 ,  G01N33/48 ,  G05B23/02

CPC分类号： G01D1/16 ,  B01J19/0006 ,  B01J19/0093 ,  B01J2219/00195 ,  B01J2219/0022 ,  B01J2219/00229 ,  B01J2219/0095 ,  B01L3/5027 ,  B01L7/52 ,  G05B23/0237

摘要： A system operable to monitoring bio/chemical activities includes a first measurement probe, a second measurement probe and a comparator. The first measurement probe is operable to interrogate one or more physical properties of a sample at a first location of the sample, and to output, in response, a first measurement signal. The second measurement probe is operable to interrogate one or more physical properties of the sample at a second location of the sample, and to output, in response, a second measurement signal. The comparator is coupled to receive the first and second measurement signals, the comparator configured to output a difference signal comprising the difference between the first and second measurement signals, the difference signal corresponding to the difference in one or more bio/chemical activities occurring at the first location of the sample relative to the second location of the sample.

摘要翻译： 可操作以监测生物/化学活动的系统，包括：第一测定试样，第二测量探针和一个比较器。 第一测量探针是可操作的，样品的第一位置询问的样品的一种或多种物理性质，并输出，作为响应，第一测量信号。 第二测量探针是可操作以在所述样品的第二位置询问样品的一种或多种物理性质，并输出，作为响应，第二测量信号。 该比较器被耦合以接收所述第一和第二测量信号，被配置为输出包括所述第一和第二测量信号之间的差的差信号，所述差信号对应于该差值在一个或多个生物的比较器/化学活动处出现 相对于样品的第二位置的样品的第一位置。