专利检索 ap:("PUBLIC UNIV CORP YOKOHAMA CITY" OR "UNIV NAGASAKI" OR "UNIV NAGOYA CITY") AND inv:"GOSHIMA YOSHIO" 第 1 页

1.

发明公开
USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) 审中-公开
标题翻译：使用MSIN3B结合化合物特异性结合神经元限制性沉默因子（NRSF）

公开(公告)号：EP2535059A4

公开(公告)日：2014-03-12

申请号：EP11742245

申请日：2011-02-09

申请人： PUBLIC UNIV CORP YOKOHAMA CITY , UNIV NAGASAKI , UNIV NAGOYA CITY

发明人： NISHIMURA YOSHIFUMI , NAGADOI ARITAKA , HIRAO YUUKA , GOSHIMA YOSHIO , YAMASHITA NAOYA , MIYATA NAOKI , SUZUKI TAKAYOSHI , HIRAISHI RYUTA , UEDA HIROSHI

IPC分类号： A61K45/00 , A61K31/445 , A61P3/10 , A61P9/00 , A61P17/00 , A61P25/14 , A61P25/16 , A61P25/28 , A61P35/00 , A61P37/08 , C07D211/14 , C07D211/16

CPC分类号： C07D211/16 , A61K31/445 , C07C233/65 , C07C233/66 , C07C2601/14 , C07D207/06 , C07D211/10 , C07D211/14 , C07D211/96 , C07D223/04 , C07D225/02 , C07D265/30 , C07D295/192

2.

发明公开
METHOD FOR DETECTING NEUROLOGICAL DISEASE ACCOMPANIED BY INFLAMMATION AND/OR DEMYELINATION 审中-公开
标题翻译：方法A与炎症和/或相关的神经系统疾病脱髓鞘检测

公开(公告)号：EP2924437A4

公开(公告)日：2016-08-31

申请号：EP13856671

申请日：2013-11-21

申请人： PUBLIC UNIV CORP YOKOHAMA CITY

发明人： TAKEI KOHTARO , TAKAHASHI KEITA , SUZUKI YUME , GOSHIMA YOSHIO

IPC分类号： G01N33/68 , C07K14/47

CPC分类号： G01N33/6896 , G01N2333/78 , G01N2800/2835 , G01N2800/285 , G01N2800/52 , G01N2800/54 , G01N2800/7095

摘要： Novel means useful for definitive diagnosis of a neurological disease accompanied by at least one of inflammation and demyelination, such as multiple sclerosis or neuromyelitis optica, is disclosed. The method for detecting a neurological disease (excluding cerebral infarction) accompanied by at least one of inflammation and demyelination provided by the present invention comprises measuring Crtac1B protein in a sample separated from a subject. The presence of the neurological disease is detected based on a low value of the Crtac1B protein level.