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公开(公告)号：EP3176270A1
公开(公告)日：2017-06-07
申请号：EP16203301.3
申请日：2008-05-23
IPC分类号： C12Q1/68
摘要： The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.
摘要翻译： 本发明涉及预后标志物和预后特征，以及用于确定患者中癌症预后的组合物和方法，特别是用于黑素瘤。 具体而言，本发明涉及基于标志物和标志物的标志物和基因标志物，用于预测癌症（例如黑素瘤）发展风险的遗传和蛋白质标志物的用途。 在各个方面，本发明提供基于预后癌症标志物，特别是黑素瘤预后标志物的方法，组合物，试剂盒和装置，以辅助癌症的预后和治疗。
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公开(公告)号：EP2158332B1
公开(公告)日：2017-01-18
申请号：EP08766967.7
申请日：2008-05-23
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G06F19/00 , G16H50/30
摘要： The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.
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公开(公告)号：EP2158332A1
公开(公告)日：2010-03-03
申请号：EP08766967.7
申请日：2008-05-23
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G06F19/00 , G16H50/30
摘要： The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.
摘要翻译： 本发明涉及预后标志物和预后特征，以及用于确定患者癌症预后的组合物和方法，特别是黑素瘤。 具体而言，本发明涉及遗传和蛋白质标记物用于基于标记物的标记和标记物来预测癌症进展风险（例如黑素瘤）的用途。 在各个方面，本发明提供了基于预后癌症标志物，特别是黑素瘤预后标志物的方法，组合物，试剂盒和装置，以帮助癌症的预后和治疗。
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5.发明授权NOVEL MARKER FOR DETECTION OF BLADDER CANCER AND/OR INFLAMMATORY CONDITIONS OF THE BLADDER 有权用于检测膀胱的膀胱癌和/或炎症状况的新标志
公开(公告)号：EP2638398B1
公开(公告)日：2018-01-24
申请号：EP11846559.0
申请日：2011-11-11
申请人： Pacific Edge Limited
IPC分类号： G01N33/574 , C12Q1/68 , G01N33/68
CPC分类号： C12Q1/6886 , C12Q2600/158 , G01N33/566 , G01N33/57407 , G01N2333/7155 , G06F19/20
摘要： This invention relates to the use of human neutrophil marker interleukin 8 receptor B (IL8Rb) for detection of bladder cancer, and more particularly to the use of EL8Rb for discriminating between transitional cell carcinoma of the bladder (TCC) and inflammatory conditions of the bladder.
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公开(公告)号：EP2430193B1
公开(公告)日：2016-03-09
申请号：EP10775152.1
申请日：2010-05-14
申请人： Pacific Edge Limited
发明人： GUILFORD, Parry John
CPC分类号： G01N33/57446 , C12Q1/6886 , C12Q2600/158 , C12Q2600/16 , G01N2333/47 , G01N2333/4725 , G06F19/20
摘要： Early detection of tumors is a major determinant of survival of patients suffering from tumors, including gastric tumors. Members of the GTM gene family can be differentially expressed in gastric tumor tissue, and thus can be used as markers for the detection of gastric and other types of cancer. The present invention provides for novel GTMs for the detection of tumors, including gastric tumors, and in particular human zymogen granule protein 16 (ZG16). The GTMs can be used in isolation or together with other known GTMs to provide for novel signatures to be used in the detection of tumors, including gastric tumors.
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