公开(公告)号：EP0610755A1

公开(公告)日：1994-08-17

申请号：EP94101292.4

申请日：1994-01-28

申请人： Pall Corporation

发明人： Buttery, Roger Alexander ,  Cook, Nigel Jeremy Desmond ,  Gutman, Richard Gay, Dr. ,  Troth, Harbey Graham, Dr.

IPC分类号： B01D67/00 ,  B01D71/56

CPC分类号： B01D67/0093 ,  B01D63/067 ,  B01D69/04 ,  B01D69/141

摘要： A method for producing a generally cylindrical filter medium and a filter element employing said medium is provided, where the filter medium is pleated and comprises a multi-layered structure of overlapping layers of membrane material. The filter element is particularly suited for separating immunoglobulin from a fluid, where the filter medium is first treated with an activating agent to from activated sites on the membrane surface. The thus treated membrane is then again treated with a protein, specific to a certain immunoglobulin. The fluid containing the immunoglobulin to be separated is then passed through the filter medium, whereby the immunoglobulin is separated cleanly at the activated sites.

摘要翻译： 提供了一种用于生产大致圆柱形的过滤介质的方法和使用所述介质的过滤元件，其中过滤介质被打褶并且包括膜材料的重叠层的多层结构。 过滤元件特别适用于从流体中分离免疫球蛋白，其中过滤介质首先用活化剂处理至膜表面上的活化位点。 然后用如此处理的膜再次用特定于某种免疫球蛋白的蛋白质处理。 然后将含有待分离的免疫球蛋白的液体通过过滤介质，由此免疫球蛋白在活化位置处被干净地分离。