Means and method for hormonal contraception
    1.
    发明公开
    Means and method for hormonal contraception 有权
    激素避孕的手段和方法

    公开(公告)号:EP1293210A1

    公开(公告)日:2003-03-19

    申请号:EP01201945.1

    申请日:2001-05-23

    IPC分类号: A61K31/57 A61P15/18

    CPC分类号: A61K31/56 A61K31/565

    摘要: The present invention is concerned with a kit containing a plurality of hormone units for use in a contraceptive method which consists of two alternating consecutive phases, sometimes referred to as a sequential method or sequential regimen. More particularly the present invention relates to a kit containing a plurality of daily hormone units for use in a contraceptive method which consists of two alternating consecutive phases - an estrogenic and a progestogenic phase - of administering a sequence of said hormone units to a female of childbearing capability, the plurality of daily hormone units consisting of:

    a) one or more daily hormone units, for use during the estrogenic phase, containing synthetic estrogen or a combination of synthetic estrogen and biogenic estrogen in a therapeutically effective amount to inhibit ovulation and
    b) at least 10 daily hormone units, for use during the progestogenic phase, containing a combination of biogenic estrogen and progestogen in a therapeutically effective amount to inhibit ovulation and to transform the endometrium from a proliferative into a secretory state.

    摘要翻译: 本发明涉及包含多种激素单位的试剂盒,用于由两个交替连续阶段组成的避孕方法,有时称为连续方法或顺序方案。 更具体地说,本发明涉及包含多种用于避孕方法的每日激素单位的试剂盒,该方法由两个交替的连续阶段组成 - 雌激素阶段和孕激素阶段 - 将一系列所述激素单位给予生育的女性 能力,所述多个每日激素单位由以下成分组成:a)在雌激素阶段期间使用的一种或多种每日激素单位,其含有治疗有效量的合成雌激素或合成雌激素和生物源性雌激素的组合以抑制排卵,和b) 至少10个用于孕激素期的每日激素单位,其含有治疗有效量的生物雌激素和孕激素的组合,以抑制排卵并将子宫内膜从增殖性转化为分泌状态。