OPTICAL SENSORS FOR MONITORING BIOPHARMACEUTICAL SOLUTIONS IN SINGLE-USE CONTAINERS
    2.
    发明公开
    OPTICAL SENSORS FOR MONITORING BIOPHARMACEUTICAL SOLUTIONS IN SINGLE-USE CONTAINERS 审中-公开
    OPTISCHE SENSOREN ZURÜBERWACHUNGBIOPHARMAZEUTISCHERLÖSUNGENIN EINMAL-BEHÄLTERN

    公开(公告)号:EP2689237A1

    公开(公告)日:2014-01-29

    申请号:EP12716130.5

    申请日:2012-03-14

    IPC分类号: G01N21/85 G01N21/03 G01N21/53

    摘要: Disposable, pre-sterilized, and pre-calibrated, pre-validated sensors are provided. The sensor comprises a disposable fluid conduit or reactor bag and a reusable sensor assembly. An optical bench or inset optical component is integrated within the disposable fluid conduit or bioreactor bag, which provides an optical light path through the conduit or bag. These sensors are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the disposable fluid conduit or bag and on the reusable sensor assembly. Methods for calibrating the sensor and for determining a target property of an unknown fluid are also disclosed. The devices, systems and methods relating to the sensor are suitable for and can be outfitted for turbidity sensing.

    摘要翻译: 提供了一次性,预消毒和预校准的预验证传感器部件。 传感器组件与具有一次性流体导管或生物反应器袋和可重复使用的传感器组件的传感器系统相互作用。 组件可以包括设计成集成在一次性流体导管或生物反应器袋内的光学台或嵌入式光学部件或模块,其提供穿过导管或袋的光学光路。 传感器系统被设计为将诸如校准和生产信息的传感器特定信息存储在一次性流体导管或袋上以及可重复使用的传感器组件上的非易失性存储器芯片中。 还公开了用于校准传感器和用于确定未知流体的目标性质的方法。 与传感器相关的设备,系统和方法适用于并可用于浊度检测。

    RISK-MANAGED, SINGLE-USE, PRE-CALIBRATED, PRE-STERILIZED SENSORS FOR USE IN BIO-PROCESSING APPLICATIONS
    4.
    发明公开
    RISK-MANAGED, SINGLE-USE, PRE-CALIBRATED, PRE-STERILIZED SENSORS FOR USE IN BIO-PROCESSING APPLICATIONS 有权
    预校准的预消毒和效催化剂风险管理FOR USE IN BIOVERARBEITUNGSANWENDUNGEN

    公开(公告)号:EP2893476A2

    公开(公告)日:2015-07-15

    申请号:EP13765569.2

    申请日:2013-09-05

    摘要: Single-use, pre-sterilized, and pre-calibrated, pre-validated sensors are provided. These sensors are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the sensor or in a barcode printed on the sensor. These sensors may be utilized with in-line systems, closed fluid circuits, bioprocessing systems, or systems which require an aseptic environment while avoiding or reducing cleaning procedures and quality assurance variances. The sensors exhibit both their primary sensing function such as conductivity, pH level, dissolved oxygen, pressure or temperature, as well as at least one secondary sensing function of risk management or risk mitigation.

    摘要翻译: 单次使用的,预先灭菌的,和预校准,提供了预先验证的传感器。 这些传感器被设计用来存储传感器特定信息,颜色:如在传感器上或印在传感器条形码的非易失性存储器芯片的校准和生产信息。 这些传感器可以与在线系统一起使用,封闭的流体回路,生物处理系统,或需要以无菌环境,同时避免或减少清洁程序和质量保证系统的差异。 传感器表现出这两种它们的主要感测功能:如电导率,pH值水平,溶解氧,压力或温度,以及风险管理或降低风险的至少一个次级感测功能。

    SINGLE-USE PH SENSORS IN BIOREACTORS, BIOTECH PURIFICATION AND BIO PROCESSING
    7.
    发明公开
    SINGLE-USE PH SENSORS IN BIOREACTORS, BIOTECH PURIFICATION AND BIO PROCESSING 审中-公开
    在生物反应器,生物技术和生物加工清洗一次性pH传感器

    公开(公告)号:EP2973103A2

    公开(公告)日:2016-01-20

    申请号:EP14722834.0

    申请日:2014-03-12

    CPC分类号: G01N27/302 G01N27/4167

    摘要: Presteralized manifolds having disposable multifunctional sensors are provided which are designed for sterile packaging and single-use approaches. These manifolds, which have disposable tubing and flexible-wall containers and are adapted to interact with other equipment which can be operated by a controller and a flow-imparting unit, provide automated and accurate delivery or purification of biotechnology fluid. The disposable sensor monitors pH, oxygen and electrical conductivity, alone or in combination, that interact with the controller or are connected to a separate user interface. Disposable sensor components and re-usable components can be dockable with each other.