公开(公告)号：EP2657697A3

公开(公告)日：2014-02-19

申请号：EP13177423.4

申请日：2009-01-26

申请人： PerkinElmer Health Sciences, Inc. ,  Wallac OY ,  The Fetal Medicine Foundation ,  Nicolaides, Kypros

发明人： Nicolaides, Kypros ,  Cuckle, Howard ,  Ahola, Tarja ,  Poon, Leona

IPC分类号： G01N33/00

CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

公开(公告)号：EP2657697A2

公开(公告)日：2013-10-30

申请号：EP13177423.4

申请日：2009-01-26

申请人： PerkinElmer Health Sciences, Inc. ,  Wallac OY ,  The Fetal Medicine Foundation ,  Nicolaides, Kypros

发明人： Nicolaides, Kypros ,  Cuckle, Howard ,  Ahola, Tarja ,  Poon, Leona

IPC分类号： G01N33/00

CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

摘要翻译： 本公开涉及用于确定怀孕个体基于来自个体和生物物理标记的生物样品中某些生物化学标记物的量来发展先兆子痫的风险的方法，医学概况，试剂盒和装置。 本公开还涉及用于确定怀孕个体携带具有染色体异常的胎儿的风险的方法，医学概况，试剂盒和装置，其基于来自个体和生物物理标记的生物样品中某些生化标志物的量。

公开(公告)号：EP2657697B1

公开(公告)日：2016-06-08

申请号：EP13177423.4

申请日：2009-01-26

申请人： Wallac Oy ,  The Fetal Medicine Foundation

发明人： Nicolaides, Kypros ,  Cuckle, Howard

IPC分类号： G01N33/00

CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

公开(公告)号：EP3109322A1

公开(公告)日：2016-12-28

申请号：EP16173417.3

申请日：2009-01-26

申请人： Wallac Oy ,  The Fetal Medicine Foundation

发明人： Cuckle, Howard ,  Nicolaides, Kypros ,  Ahola, Tarja

IPC分类号： C12Q1/16

CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

摘要翻译： 本公开涉及用于确定怀孕个体基于来自个体和生物物理标记的生物样品中某些生物化学标记物的量来发展先兆子痫的风险的方法，医学概况，试剂盒和装置。 本公开还涉及用于确定怀孕个体携带具有染色体异常的胎儿的风险的方法，医学概况，试剂盒和装置，其基于来自个体和生物物理标记的生物样品中某些生化标志物的量。