专利检索 ap:("Pfizer Inc.") AND inv:"CUI, Jingrong Jean" 第 1 页

1.

发明公开
TROPOMYOSIN-RELATED KINASE INHIBITORS CONTAINING BOTH A 1H-PYRAZOLE AND A PYRIMIDINE MOIETY 审中-公开
标题翻译： TROPOMYSIN-VERWANDTE KINASEINHIBITOREN MIT EINER 1H-PYRAZOL- SOWIE PYRIMIDINEINHEIT

公开(公告)号：EP3131891A1

公开(公告)日：2017-02-22

申请号：EP15723557.3

申请日：2015-04-01

申请人： Pfizer Inc.

发明人： BAGAL, Sharanjeet Kaur , CUI, Jingrong Jean , GREASLEY, Samantha Elizabeth , LUNNEY, Elizabeth Ann , MCALPINE, Indrawan James , NAGATA, Asako , NINKOVIC, Sacha , OMOTO, Kiyoyuki , SKERRATT, Sarah Elizabeth , STORER, Robert Ian , WARMUS, Joseph Scott

IPC分类号： C07D401/12 , C07D401/14 , A61K31/415

CPC分类号： C07D401/14 , A61K31/4439 , C07D401/12

摘要： and their prodrugs and pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as TrkA antagonists.

摘要翻译： 本发明涉及式（I）化合物及其前药和药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为TrkA拮抗剂。

2.

发明公开
TROPOMYOSIN-RELATED KINASE INHIBITORS 审中-公开
标题翻译： TROPOMYOSIN-ASSOZIIERTE KINASEINHIBITOREN

公开(公告)号：EP3140298A1

公开(公告)日：2017-03-15

申请号：EP15728610.5

申请日：2015-04-27

申请人： Pfizer Inc.

发明人： BAGAL, Sharanjeet Kaur , CUI, Jingrong Jean , GREASLEY, Samantha Elizabeth , LUNNEY, Elizabeth Ann , MCALPINE, Indrawan James , NAGATA, Asako , NINKOVIC, Sacha , OMOTO, Kiyoyuki , SKERRATT, Sarah Elizabeth , STORER, Robert Ian , WARMUS, Joseph Scott

IPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D413/14 , A61K31/4439 , A61P29/00 , A61P35/00

CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D413/14

摘要： The present invention relates to compounds of Formula I and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as TrkA antagonists.

摘要翻译： 本发明涉及式I化合物及其药学上可接受的盐，其中取代基如本文所述，及其在药物中的用途，特别是作为TrkA拮抗剂。

3.

发明公开
PYRAZOLE COMPOUNDS AND THEIR USE AS RAF INHIBITORS 审中-公开
标题翻译：吡唑化合物及其作为RAF抑制剂的用途

公开(公告)号：EP2183243A2

公开(公告)日：2010-05-12

申请号：EP08788934.1

申请日：2008-07-21

申请人： Pfizer Inc.

发明人： CUI, Jingrong Jean , DEAL, Judith Gail , GU, Danlin , GUO, Chuangxing , JOHNSON, Mary Catherine , KANIA, Robert Steven , KEPHART, Susan Elizabeth , LINTON, Maria Angelica , MCALPINE, Indrawan James , PAIRISH, Mason Alan , PALMER, Cynthia Louise

IPC分类号： C07D401/14 , C07D403/14 , C07D471/04 , C07D487/04 , A61K31/4439 , A61K31/506 , A61P35/00

CPC分类号： C07D471/04 , C07D401/14 , C07D403/14 , C07D487/04

摘要： The present invention is directed to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.