公开(公告)号：EP1187826A1

公开(公告)日：2002-03-20

申请号：EP00920969.3

申请日：2000-05-03

申请人： Pfizer Products Inc.

发明人： GANT, Thomas, George,Pfizer Inc. ,  NOE, Mark, Carl,Pfizer Inc.

IPC分类号： C07D333/38 ,  C07D275/03 ,  C07D231/44 ,  C07D409/12 ,  C07D417/04 ,  A61K31/425 ,  A61K31/415 ,  A61K31/381 ,  A61P35/00

CPC分类号： C07D275/03 ,  C07D231/44 ,  C07D333/38 ,  C07D409/12 ,  C07D417/04

摘要： The present invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein Z, X, X?1, R1, R2 and R3¿ are as defined herein as it relates to pharmaceutical compositions containing the above compounds for the treatment of disorders mediated by angiogenesis in mammals by administration of the above compounds.