公开(公告)号：EP1414526A2

公开(公告)日：2004-05-06

申请号：EP02731524.1

申请日：2002-04-25

申请人： Pharmacia Corporation

发明人： MCKEARN, John, P. ,  GORDON, Gary, B. ,  CUNNINGHAM, James, J. ,  GATELY, Stephen, T. ,  KOKI, Alane, T. ,  MASFERRER, Jaime, L.

IPC分类号： A61P35/00 ,  A61K45/06

CPC分类号： A61K31/00 ,  A61K31/135 ,  A61K31/415 ,  A61K31/42 ,  A61K31/445 ,  A61K31/454 ,  A61K31/505 ,  A61K31/506 ,  A61K31/5685 ,  A61K31/675 ,  A61K33/24 ,  A61K41/00 ,  A61K41/0038 ,  A61K45/06 ,  A61K2300/00

摘要： The present invention provides combinations of a DNA topoisomerase I inhibiting agent and a selective COX-2 inhibiting agent for preventing, treating, and/or reducing the risk of developing a neoplasia disorder in a mammal.