专利检索 ap:("Pharmacyclics, LLC") AND inv:"LOURY, David" 第 1 页

1.

发明授权
INHIBITORS OF BRUTON'S TYROSINE KINASE 有权

公开(公告)号：EP2139487B1

公开(公告)日：2015-11-11

申请号：EP08744513.6

申请日：2008-03-27

申请人： Pharmacyclics LLC

发明人： HONIGBERG, Lee , VERNER, Erik , BUGGY, Joseph, J. , LOURY, David , CHEN, Wei

IPC分类号： A61K31/52 , A61P29/00 , A61P35/00 , A61K31/519 , C07D253/06 , C07D487/04 , C07D473/34

CPC分类号： C07D487/04 , A61K31/52 , C07D471/04 , C12Q1/485 , G01N33/57426 , G01N2440/14 , G01N2500/00

2.

发明公开
INHIBITORS OF BRUTON'S TYROSINE KINASE FOR THE TREATMENT OF SOLID TUMORS 审中-公开
标题翻译：酪氨酸激酶抑制剂治疗实体肿瘤

公开(公告)号：EP3311818A2

公开(公告)日：2018-04-25

申请号：EP17191704.0

申请日：2009-07-16

申请人： Pharmacyclics, LLC

发明人： HONIGBERG, Lee , VERNER, Erik , BUGGY, Joseph , LOURY, David , CHEN, Wei

IPC分类号： A61K31/52 , A61P35/00 , A61K31/519 , A61K31/00 , A61K31/675 , A61K31/704 , A61K33/24 , A61K31/19 , A61K31/337

CPC分类号： A61K31/519 , A61K31/00 , A61K31/337 , A61K31/52 , A61K31/675 , A61K31/704 , A61K33/24 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2300/00 , A61K31/19

摘要： Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.

摘要翻译： 本文描述了不可逆的Btk抑制剂化合物，以及使用此类不可逆抑制剂治疗以实体瘤的存在或发展为特征的疾病和病症的方法。

3.

发明授权
INHIBITORS OF BRUTON'S TYROSINE KINASE FOR THE TREATMENT OF SOLID TUMORS 有权

公开(公告)号：EP2307025B1

公开(公告)日：2017-09-20

申请号：EP09798770.5

申请日：2009-07-16

申请人： Pharmacyclics LLC

发明人： HONIGBERG, Lee , VERNER, Erik , BUGGY, Joseph , LOURY, David , CHEN, Wei

IPC分类号： A61K31/52 , A61P35/00 , A61K31/519 , A61K31/00

CPC分类号： A61K31/519 , A61K31/00 , A61K31/337 , A61K31/52 , A61K31/675 , A61K31/704 , A61K33/24 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2300/00 , A61K31/19

摘要： Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.

4.

发明公开
INHIBITORS OF BRUTON'S TYROSINE KINASE FOR THE TREATMENT OF SOLID TUMORS 审中-公开

公开(公告)号：EP3311818A3

公开(公告)日：2018-07-18

申请号：EP17191704.0

申请日：2009-07-16

申请人： Pharmacyclics, LLC

发明人： HONIGBERG, Lee , VERNER, Erik , BUGGY, Joseph , LOURY, David , CHEN, Wei

IPC分类号： A61K31/52 , A61P35/00 , A61K31/519 , A61K31/00 , A61K31/675 , A61K31/704 , A61K33/24 , A61K31/19 , A61K31/337

CPC分类号： A61K31/519 , A61K31/00 , A61K31/337 , A61K31/52 , A61K31/675 , A61K31/704 , A61K33/24 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2300/00 , A61K31/19

摘要： Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.