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1.发明公开
公开(公告)号：EP4115883A1
公开(公告)日：2023-01-11
申请号：EP21764422.8
申请日：2021-03-04
发明人： YOON, Jeong Hyeok , NAM, Ky Youb
IPC分类号： A61K31/4535 , A61K33/243 , A61K31/337 , A61K31/4745 , A61K31/502 , A61P35/00 , A23L33/10
摘要： The present invention relates to a composition for preventing, ameliorating, or treating ovarian cancer, the composition containing a 2,3,5-substituted thiophene compound. The composition has excellent inhibitory activity against the proliferation of ovarian cancer, and thus may be effectively used for preventing, ameliorating, or treating ovarian cancer.
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2.发明公开
公开(公告)号：EP4190331A1
公开(公告)日：2023-06-07
申请号：EP21850952.9
申请日：2021-07-30
发明人： SIM, Tae Bo , CHOI, Seung Hye , CHO, Han Na , KIM, Nam Kyoung , HUR, Woo Young , SONG, Chi Man , NAM, Ky Youb , YOON, Jeong Hyeok
IPC分类号： A61K31/4535 , A61P35/00 , A23L33/10
摘要： The present invention relates to the use of a 2,3,5-substituted thiophene compound for the prevention, amelioration or treatment of gastrointestinal stromal tumor. The 2,3,5-substituted thiophene compound exhibits high inhibitory activity against the growth of gastrointestinal stromal tumor, and thus may be effectively used for the prevention, amelioration or treatment of gastrointestinal stromal tumor.
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公开(公告)号：EP3804719A1
公开(公告)日：2021-04-14
申请号：EP19812646.8
申请日：2019-05-29
发明人： YOON, Jeong Hyeok , NAM, Ky Youb
IPC分类号： A61K31/4535 , A61K41/00 , A61P35/00
摘要： The present disclosure relates to a composition for enhancing radiotherapy. The composition may increase the sensitivity of cancer cells to radiation, and thus may be advantageously used to enhance the effect of radiotherapy.
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4.发明公开
公开(公告)号：EP3804718A1
公开(公告)日：2021-04-14
申请号：EP19811107.2
申请日：2019-05-29
发明人： YOON, Jeong Hyeok , NAM, Ky Youb
IPC分类号： A61K31/4535 , A61K31/282 , A61K31/502 , A23L33/10 , A61P35/00
摘要： A composition for preventing, ameliorating or treating breast cancer, the composition containing a 2,3,5-substituted thiophene compound according to one embodiment of the present disclosure has an excellent activity of inhibiting the proliferation of breast cancers, particularly triple-negative breast cancer and Herceptin-resistant breast cancer, which have high mortality because there has yet been no effective therapeutic method therefor. Thus, the composition may be advantageously used for the prevention, amelioration or treatment of breast cancer.
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公开(公告)号：EP4417205A1
公开(公告)日：2024-08-21
申请号：EP22881411.7
申请日：2022-10-14
申请人： Pharos Ibio Co., Ltd
发明人： YOON, Jeong Hyeok , NAM, Ky Youb
IPC分类号： A61K31/496 , A61K31/635 , A61K31/7068 , A61K31/706 , A61K45/06 , A61P35/02
CPC分类号： A61K31/635 , A61K31/7068 , A61P35/02 , A61K31/706 , A61K45/06 , A61K31/496
摘要： The present invention relates to a composition for co-administration containing a 2,3,5-substituted thiophene compound. The composition has excellent inhibitory activity against cancer cells related to leukemia compared to treatment with the 2,3,5-substituted thiophene compound alone or an anticancer drug alone, and thus may be useful for the prevention, amelioration or treatment of leukemia.
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6.发明公开
公开(公告)号：EP4190330A1
公开(公告)日：2023-06-07
申请号：EP21849180.1
申请日：2021-07-30
发明人： SIM, Tae Bo , CHOI, Seung Hye , CHO, Han Na , HUR, Woo Young , SONG, Chi Man , NAM, Ky Youb , YOON, Jeong Hyeok
IPC分类号： A61K31/4535 , A61P3/04 , A23L33/10
摘要： The present invention relates to the use of a 2,3,5-substituted thiophene compound for the prevention, amelioration or treatment of mastocytosis. The 2,3,5-substituted thiophene compound has excellent inhibitory activity against the growth of mastocytosis cells and against an inflammatory response caused by mastocytosis, and thus may be effectively used for the prevention, amelioration or treatment of mastocytosis.
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