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    SEEDED PRECIPITATION OF POLYPEPTIDES
    3.
    发明公开
    SEEDED PRECIPITATION OF POLYPEPTIDES 审中-公开

    公开(公告)号：EP4050017A1

    公开(公告)日：2022-08-31

    申请号：EP21158984.1

    申请日：2021-02-24

    申请人： PreOmics GmbH

    发明人： KULAK, Nils A. ,  JOHANSSON, Sebastian H. ,  HARTINGER, Katrin

    IPC分类号： C07K1/30 ,  G01N33/68

    摘要： The present invention relates to a method of processing or fractionating a sample comprising proteins, polypeptides and/or peptides, said method comprising (a) changing the physicochemical conditions of said sample; and (b) performing one or both of the following (i) and (ii): (i) adding solid particulate matter to said sample; and (ii) performing said method in a vessel with a rough surface; wherein steps (a) and (b) can be effected concomitantly or in any order; and wherein said processing or fractionating yields one or more first fractions of proteins, polypeptides and/or peptides as a precipitate on said particulate matter and/or said inhomogeneous surface, and a second fraction of proteins, polypeptides and/or peptides remaining in a supernatant.