公开(公告)号：EP2604598A1

公开(公告)日：2013-06-19

申请号：EP12198526.1

申请日：2008-04-25

申请人： Purdue Pharma L.P. ,  Shionogi & Co., Ltd.

发明人： Tafesse, Laykea ,  Kurose, Noriyuki

IPC分类号： C07D401/04 ,  C07D401/14 ,  A61K31/4545 ,  A61P23/00 ,  C07D417/12 ,  C07D417/14

CPC分类号： C07D401/04 ,  C07D213/61 ,  C07D213/72 ,  C07D213/74 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D407/14 ,  C07D417/12 ,  C07D417/14

摘要： The invention relates to compounds of formula I

and pharmaceutically acceptable derivatives thereof, compositions comprising an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, UI, an ulcer, IBD and IBS, comprising administering to an animal in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof.

摘要翻译： 本发明涉及式I化合物及其药学上可接受的衍生物，包含有效量的式I化合物或其药学上可接受的衍生物的组合物，以及用于治疗或预防诸如疼痛，UI，溃疡，IBD的病症的方法 和IBS，包括向有需要的动物施用有效量的式I化合物或其药学上可接受的衍生物。

公开(公告)号：EP2604598B1

公开(公告)日：2016-04-06

申请号：EP12198526.1

申请日：2008-04-25

申请人： Purdue Pharma L.P. ,  Shionogi & Co., Ltd.

发明人： Tafesse, Laykea ,  Kurose, Noriyuki

IPC分类号： C07D401/04 ,  C07D401/14 ,  A61K31/4545 ,  A61P23/00 ,  C07D417/12 ,  C07D417/14 ,  C07D213/61 ,  C07D213/74

CPC分类号： C07D401/04 ,  C07D213/61 ,  C07D213/72 ,  C07D213/74 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D407/14 ,  C07D417/12 ,  C07D417/14

摘要： The invention relates to compounds of formula I and pharmaceutically acceptable derivatives thereof, compositions comprising an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, UI, an ulcer, IBD and IBS, comprising administering to an animal in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof.

公开(公告)号：EP2604599A1

公开(公告)日：2013-06-19

申请号：EP13155157.4

申请日：2008-04-25

申请人： Purdue Pharma LP ,  Shionogi & Co., Ltd.

发明人： Tafesse, Laykea ,  Kurose, Noriyuki

IPC分类号： C07D401/04 ,  C07D401/14 ,  A61K31/4545 ,  A61P23/00 ,  C07D417/12 ,  C07D417/14

CPC分类号： C07D401/04 ,  C07D213/61 ,  C07D213/72 ,  C07D213/74 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D407/14 ,  C07D417/12 ,  C07D417/14

摘要： The invention relates to compounds of formula I

and pharmaceutically acceptable derivatives thereof, compositions comprising an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, UI, an ulcer, IBD and IBS, comprising administering to an animal in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof.

摘要翻译： 本发明涉及式I化合物及其药学上可接受的衍生物，包含有效量的式I化合物或其药学上可接受的衍生物的组合物，以及治疗或预防诸如疼痛，UI，溃疡，IBD 包括给予有需要的动物有效量的式I化合物或其药学上可接受的衍生物。