公开(公告)号：EP1605960A2

公开(公告)日：2005-12-21

申请号：EP04720417.7

申请日：2004-03-12

申请人： REPLIGEN CORPORATION

发明人： BOISMENU, Richard ,  RUSCHE, James, R. ,  GOULET, Martin

IPC分类号： A61K38/00

CPC分类号： A61K38/2235

摘要： The invention is based, in part, on the discovery that secretin and secretin analogs can be used to treat affective disorders that include symptoms of anxiety. Secretin and secretin analogs can be administered to patients to treat affective disorders, such as mood, psychotic, mental, substance-abuse withdrawal, eating, and sexual disorders, as well as other disorders with attendant sensory processing dysfunction, including symptoms of anxiety and/or fear. In addition, secretin and secretin analogs can be administered to improve cognition, including learning and memory, as well as to lessen the effects of conditioned startle. Secretin has the added benefit of causing no negative side effects upon administration and being easy to administer.