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1.发明授权Novel peptides, their use as immuno suppressants and processes for their preparation 失效肽，其作为免疫Suppressanten及其制备方法的使用。
公开(公告)号：EP0348086B1
公开(公告)日：1995-03-15
申请号：EP89305931.1
申请日：1989-06-13
发明人： Schön, István, Dr. , Nyeki, Olga, nee Kuprina , Kisfaludy, Lajos, Dr. , Denes, László, Dr. , Hajos, György, Dr. , Szporny, László, Dr.
CPC分类号： C07K5/0817 , A61K38/00 , C07K5/06086 , C07K5/0815 , C07K5/1019
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2.发明公开Novel peptides, their use as immuno suppressants and processes for their preparation 失效新型肽，作为免疫抑制剂及其制备方法使用
公开(公告)号：EP0348086A3
公开(公告)日：1990-09-12
申请号：EP89305931.1
申请日：1989-06-13
发明人： Schön, István, Dr. , Nyeki, Olga, nee Kuprina , Kisfaludy, Lajos, Dr. , Denes, László, Dr. , Hajos, György, Dr. , Szporny, László, Dr.
CPC分类号： C07K5/0817 , A61K38/00 , C07K5/06086 , C07K5/0815 , C07K5/1019
摘要： The invention relates to novel peptides comprising at least the amino acids Arg, Lys and Asp and optionally Val in that order wherein either (a) at least one of these is in the D-configuration, or (b) wherein Arg is bonded to the ε-amino group of Lys or, (c) an Arg amino acid is bonded to the α- and ε-amino groups of Lys or (d) the Val is bonded to the β-carboxy group of the Asp, or any combination of the above options (a) to (d), and acid addition salts thereof and their preparations. The novel peptides are useful in the therapy of diseases where the decrease in the activity of the immune system is desirable. I
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3.发明公开Novel peptides, their use as immuno suppressants and processes for their preparation 失效Peptide，deren Verwendung als Immuno-Suppressanten und Verfahren zu deren Herstellung。
公开(公告)号：EP0348086A2
公开(公告)日：1989-12-27
申请号：EP89305931.1
申请日：1989-06-13
发明人： Schön, István, Dr. , Nyeki, Olga, nee Kuprina , Kisfaludy, Lajos, Dr. , Denes, László, Dr. , Hajos, György, Dr. , Szporny, László, Dr.
CPC分类号： C07K5/0817 , A61K38/00 , C07K5/06086 , C07K5/0815 , C07K5/1019
摘要： The invention relates to novel peptides comprising at least the amino acids Arg, Lys and Asp and optionally Val in that order wherein either (a) at least one of these is in the D-configuration, or (b) wherein Arg is bonded to the ε-amino group of Lys or, (c) an Arg amino acid is bonded to the α- and ε-amino groups of Lys or (d) the Val is bonded to the β-carboxy group of the Asp, or any combination of the above options (a) to (d), and acid addition salts thereof and their preparations. The novel peptides are useful in the therapy of diseases where the decrease in the activity of the immune system is desirable. I
摘要翻译： 本发明涉及至少包含Arg，Lys和Asp氨基酸和任选的Val的新肽，其中（a）至少一种是D-构型，或（b）其中Arg键合到 Lys的xi-氨基或（c）Arg氨基酸与Lys的α-和N-氨基键合，或（d）Val与Asp的β-羧基键合，或 上述选项（a）至（d）及其酸加成盐及其制备方法。 新型肽可用于治疗需要免疫系统活性降低的疾病。
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