专利检索 ap:("RIJKSUNIVERSITEIT GRONINGEN") AND inv:"LIU, Bin" 第 1 页

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发明公开
SMALL MOLECULE INHIBITORS OF RNA GUIDED ENDONUCLEASES 审中-公开

公开(公告)号：EP3889255A1

公开(公告)日：2021-10-06

申请号：EP20166793.8

申请日：2020-03-30

申请人： RIJKSUNIVERSITEIT GRONINGEN

发明人： HAISMA, Hidde Jacob , DÖMLING, Alexander Stephan Siegfried , LIU, Bin

IPC分类号： C12N9/22 , C12N9/99 , C07D209/00 , C12Q1/44 , A61K31/381

摘要： The present invention relates to the use of compounds of formula (I) as inhibitors of RNA guided endonucleases, e.g., Cas9 and Cpfl, and methods for the inhibition of the function of such RNA guided endonucleases, including their use in the treatment and prevention of conditions or diseases.