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公开(公告)号：EP2835648B1
公开(公告)日：2018-12-12
申请号：EP14179941.1
申请日：2014-08-05
CPC分类号： G01N33/94 , C07K16/44 , C07K2317/33 , G01N33/946 , G01N2430/00
摘要： Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.
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公开(公告)号：EP2998743B1
公开(公告)日：2018-02-21
申请号：EP15185671.3
申请日：2015-09-17
IPC分类号： G01N33/94 , C07D231/56 , C07D409/12
CPC分类号： G01N33/948 , C07D231/56 , C07D409/12 , C07K16/44
摘要： Components for enabling immunodection of indazole synthetic cannabinoids are described including immunogens, haptens, antibodies and kits.
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3.发明授权Immunoassay for cyclopropylindole based synthetic cannabinoids, metabolites and derivatives thereof 有权Cyclopropylindolbasierte免疫测定对合成大麻素，代谢物和它们的衍生物
公开(公告)号：EP2781527B1
公开(公告)日：2016-10-19
申请号：EP14160047.8
申请日：2014-03-14
CPC分类号： C07K16/44 , C07K2317/33 , G01N33/948
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公开(公告)号：EP2631231B1
公开(公告)日：2016-04-20
申请号：EP13156414.8
申请日：2013-02-22
IPC分类号： C07D295/096 , C07D295/155
CPC分类号： C07D295/155 , C07D241/04 , C07D295/096 , C07K14/47 , C07K14/765 , C07K16/44 , C07K2317/76 , G01N33/5308
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公开(公告)号：EP2626358B1
公开(公告)日：2015-09-02
申请号：EP13154614.5
申请日：2013-02-08
IPC分类号： C07D405/06 , C07K16/44 , G01N33/94
CPC分类号： G01N33/94 , C07D405/06 , C07K16/44 , G01N33/946
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公开(公告)号：EP2887070A1
公开(公告)日：2015-06-24
申请号：EP14198959.0
申请日：2014-12-18
CPC分类号： G01N33/9486 , C07C229/46 , C07K16/44 , C07K2319/92 , G01N2430/00
摘要： An immunoassay for the detection of tildine and nortilidine is described. The invention also describes antibodies and kits.
摘要翻译： 描述了用于检测白蛋白和诺替啶的免疫测定。 本发明还描述了抗体和试剂盒。
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公开(公告)号：EP2631231A1
公开(公告)日：2013-08-28
申请号：EP13156414.8
申请日：2013-02-22
IPC分类号： C07D295/096 , C07D295/155
CPC分类号： C07D295/155 , C07D241/04 , C07D295/096 , C07K14/47 , C07K14/765 , C07K16/44 , C07K2317/76 , G01N33/5308
摘要： The current invention describes novel immunogens which are used in the production of novel antibodies with unique binding properties in that they cross-react with a variety of phenylpiperazine derivatives. These antibodies enable methods and kits to detect and/or determine phenylpiperazine derivatives (for example mCPP, TFMPP and MeOPP) in an in vitro sample which are advantageous over currently available analytical methods in terms of cost, ease of use, speed and sensitivity.
摘要翻译： 本发明描述了新型免疫原，其用于生产具有独特结合特性的新型抗体，因为它们与各种苯基哌嗪衍生物交叉反应。 这些抗体使得方法和试剂盒能够在体外样品中检测和/或测定苯基哌嗪衍生物（例如mCPP，TFMPP和MeOPP），这在成本，易用性，速度和灵敏度方面优于目前可用的分析方法。
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公开(公告)号：EP2418492A1
公开(公告)日：2012-02-15
申请号：EP10172415.1
申请日：2010-08-10
CPC分类号： G01N33/948 , C07K16/44
摘要： Carisoprodol is a centrally-acting prescription drug of known abuse. Upon ingestion it is rapidly metabolised to meprobamate, also a prescription drug with abuse potential. Current immunoassays are specific for carisoprodol and therefore have a short window of detection and, furthermore, are ineffective at detecting meprobamate. The current invention, underpinned by an antibody specific for meprobamate, overcomes these deficiencies.
摘要翻译： Carisoprodol是一种中枢作用的已知滥用药物。 摄入后，它迅速代谢为甲基磺酸盐，也是具有滥用潜力的处方药。 目前的免疫测定法是特异性的，因此，对于二十二烷酮，因此具有短的检测窗口，此外，在检测甲基磺酸盐时无效。 由针对甲基磺酸盐的抗体支持的本发明克服了这些缺点。
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公开(公告)号：EP2402761A1
公开(公告)日：2012-01-04
申请号：EP10168015.5
申请日：2010-06-30
CPC分类号： G01N33/948 , C07K16/44 , C07K2317/33
摘要： The invention relates to an immunoassay method and kit for the indirect detection of chloral hydrate. The invention is underpinned by a novel immunogen that produces an antibody that is specific for the chloral hydrate metabolite trichloroethanol glucuronide. Detection and quantification of trichloroethanol glucuronide has important applications in clinical toxicology, drug facilitated crime, water testing and solvent exposure.
摘要翻译： 本发明涉及用于间接检测水合氯醛的免疫测定方法和试剂盒。 本发明由新型免疫原支持，该新型免疫原产生对水合氯醛代谢物三氯乙醇葡萄糖醛酸苷特异的抗体。 三氯乙醇葡萄糖醛酸苷的检测和定量在临床毒理学，药物促进的犯罪，水测试和溶剂暴露方面具有重要应用。
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公开(公告)号：EP2418492B1
公开(公告)日：2018-10-10
申请号：EP10172415.1
申请日：2010-08-10
CPC分类号： G01N33/948 , C07K16/44
摘要： Carisoprodol is a centrally-acting prescription drug of known abuse. Upon ingestion it is rapidly metabolised to meprobamate, also a prescription drug with abuse potential. Current immunoassays are specific for carisoprodol and therefore have a short window of detection and, furthermore, are ineffective at detecting meprobamate. The current invention, underpinned by an antibody specific for meprobamate, overcomes these deficiencies.
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