公开(公告)号：EP2424980A1

公开(公告)日：2012-03-07

申请号：EP10721379.5

申请日：2010-04-30

申请人： Redbiotec AG

发明人： JOHN, Corinne ,  SCHAUB, Christian ,  WELLNITZ, Sabine

IPC分类号： C12N7/04

CPC分类号： C12N15/86 ,  A61K2039/5256 ,  A61K2039/5258 ,  C12N7/00 ,  C12N2710/14043 ,  C12N2710/14143 ,  C12N2710/16123 ,  C12N2710/20023 ,  C12N2710/20034 ,  C12N2760/16023 ,  C12N2760/16123 ,  C12N2760/16134

摘要： The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques for production. The recombinant virus-like particles of the invention are assembled by polypeptide chains that incorporate several, in particular two or more, different epitopes which are selected either (a) from different viral strains of the same virus and/or (b) from different serotypes of the same virus and/or (c) from different viral strains specific for different hosts. These epitopes are then displayed on the particle surface.

公开(公告)号：EP4304641A1

公开(公告)日：2024-01-17

申请号：EP22714389.8

申请日：2022-03-11

申请人： Redbiotec AG

发明人： TAMBASCO STUDART, Marina ,  SCHAUB, Christian ,  JOHN, Corinne ,  BÜHLMANN, Martin ,  WROBLEWSKA, Martyna ,  WILSON, David

IPC分类号： A61K39/12 ,  C07K14/005

公开(公告)号：EP2952581A1

公开(公告)日：2015-12-09

申请号：EP15173061.1

申请日：2010-04-30

申请人： Redbiotec AG

发明人： JOHN, Corinne ,  SCHAUB, Christian ,  WELLNITZ, Sabine

IPC分类号： C12N7/04

CPC分类号： C12N15/86 ,  A61K2039/5256 ,  A61K2039/5258 ,  C12N7/00 ,  C12N2710/14043 ,  C12N2710/14143 ,  C12N2710/16123 ,  C12N2710/20023 ,  C12N2710/20034 ,  C12N2760/16023 ,  C12N2760/16123 ,  C12N2760/16134

摘要： The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques for production. The recombinant virus-like particles of the invention are assembled by polypeptide chains that incorporate several, in particular two or more, different epitopes which are selected either (a) from different viral strains of the same virus and/or (b) from different serotypes of the same virus and/or (c) from different viral strains specific for different hosts. These epitopes are then displayed on the particle surface.

摘要翻译： 本发明描述了用于疫苗，诊断工具和基于重组DNA和用于生产的细胞培养技术的研发工具的新型病毒样颗粒。 本发明的重组病毒样颗粒由多肽链组装，所述多肽链包含数个，特别是两个或多个不同的表位，其选自（a）来自相同病毒的不同病毒株和/或（b）不同血清型 的相同病毒和/或（c）来自不同宿主特异性的不同病毒株。 然后将这些表位显示在颗粒表面上。

公开(公告)号：EP4373842A2

公开(公告)日：2024-05-29

申请号：EP22757269.0

申请日：2022-07-25

申请人： Redbiotec AG

发明人： DROZ, Xuan ,  BÜHLMANN, Martin ,  TAMBASCO STUDART, Marina ,  SCHAUB, Christian ,  JOHN, Corinne ,  LOSFELD, Marie-Estelle

IPC分类号： C07K14/47

CPC分类号： C07K14/4732

公开(公告)号：EP3429619A1

公开(公告)日：2019-01-23

申请号：EP17710735.6

申请日：2017-03-14

申请人： Redbiotec AG

发明人： STERGIOU, Garyfalia ,  SCHAUB, Christian ,  JOHN, Corinne

IPC分类号： A61K39/12