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公开(公告)号:EP4031565A1
公开(公告)日:2022-07-27
申请号:EP20864423.7
申请日:2020-09-15
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公开(公告)号:EP4041757A1
公开(公告)日:2022-08-17
申请号:EP20870067.4
申请日:2020-09-25
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公开(公告)号:EP3867278A1
公开(公告)日:2021-08-25
申请号:EP19873982.3
申请日:2019-10-17
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公开(公告)号:EP3359168A1
公开(公告)日:2018-08-15
申请号:EP16854310.6
申请日:2016-10-06
IPC分类号: A61K35/17 , C07K16/28 , C07K16/46 , C12N5/00 , C12N5/0783
CPC分类号: C07K14/55 , A61K38/00 , C07K14/5443 , C07K16/1045 , C07K16/244 , C07K16/2803 , C07K16/2809 , C07K16/283 , C07K16/30 , C07K2317/22 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2319/33 , C12N5/0646
摘要: This disclosure describes engineered compounds that engage NK cells and methods of using the compounds. Generally, the compound includes an NK engaging domain, a targeting domain that selectively binds to a target cell, and an NK activating domain operably linking the NK engaging domain and the targeting domain.
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