APPARATUS AND METHODS FOR OPTICAL COHERENCE TOMOGRAPHY AND TWO-PHOTON LUMINESCENCE IMAGING

    公开(公告)号:EP2972068A2

    公开(公告)日:2016-01-20

    申请号:EP14770669.1

    申请日:2014-03-14

    IPC分类号: G01B9/02

    摘要: Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.

    摘要翻译: 本公开的示例性实施例包括组合的基于导管的光学相干断层成像 - 双光子发光(OCT-TPL)成像系统。 示例性实施方案还包括在体内具有高空间分辨率的薄盖纤维状细胞中检测并进一步表征细胞组分(例如,巨噬细胞,胶原/弹性蛋白纤维,脂滴)的分布的方法。