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公开(公告)号:EP2077113A1
公开(公告)日:2009-07-08
申请号:EP08000113.4
申请日:2008-01-04
发明人: Kurts, Christian , Burgdorf, Sven
CPC分类号: A61K31/47 , A61K31/4706
摘要: The present invention relates to an agent capable of preventing early endosome mediated antigen presentation for use in a method for treating or preventing an autoimmune disease or a transplant rejection. In a preferred embodiment, the agent, preferably primaquine, is capable of preventing early endosome trafficking towards the cell membrane.
摘要翻译: 本发明涉及能够预防早期内体介导的抗原呈递用于治疗或预防自身免疫性疾病或移植排斥的方法中的药剂。 在一个优选的实施方案中,该药剂,优选伯氨喹,能够预防早期内体体内向细胞膜的运送。