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    PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS
    2.
    发明公开
    PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS 审中-公开
    PROCESS生产光学纯和可选取代的2-（1-羟烷基）苯并吡喃-4- ON衍生物及其在药物方面的制造

    公开(公告)号：EP2844647A1

    公开(公告)日：2015-03-11

    申请号：EP13729095.3

    申请日：2013-05-03

    申请人： Rhizen Pharmaceuticals S.A.

    发明人： RAMAN, Jayaraman Venkat ,  VAKKALANKA, Swaroop Kumar Venkata Satya

    IPC分类号： C07D311/36 ,  C07D405/06

    摘要： The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives represented by formula (IA) and (IB), processes for preparing the alcohol derivatives and their use in preparing pharmaceuticals.

    摘要翻译： 本发明涉及化合物作为药物中间体是有用的，的制备方法的中间体，在方法中使用的中间体，并在药物的制备中使用的中间体。 特别地，本发明涉及对映体纯OPTIONALLY substituiertem 2-（1-羟基烷基）苯并吡喃-4-酮衍生物由式（IA）和（IB）表示，用于制备在制备药物的醇衍生物和它们的使用 ，