公开(公告)号：EP2132185A2

公开(公告)日：2009-12-16

申请号：EP08737283.5

申请日：2008-04-10

申请人： Richter Gedeon Nyrt.

发明人： BARTÁNÉ SZALAI, Gizella ,  ÁGAINÉ CSONGOR, Éva ,  DOMÁNY, György ,  GYERTYÁN, István ,  KISS, Béla ,  LASZY, Judit ,  SÁGHY, Katalin ,  SCHMIDT, Éva ,  FARKAS, Sándor ,  KOMLÓDI, Zsolt

IPC分类号： C07D239/48 ,  A61K31/506 ,  A61P25/00

CPC分类号： C07D239/48

摘要： The present invention relates to new dopamine D3 and D2 ligands of formula (I): wherein Rl, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes for preparing the same, to compositions containing the same and to their use in the treatment and/or prevention of conditions which requires modulation of dopamine receptors.

公开(公告)号：EP2132185B1

公开(公告)日：2011-08-03

申请号：EP08737283.5

申请日：2008-04-10

申请人： Richter Gedeon Nyrt.

发明人： BARTÁNÉ SZALAI, Gizella ,  ÁGAINÉ CSONGOR, Éva ,  DOMÁNY, György ,  GYERTYÁN, István ,  KISS, Béla ,  LASZY, Judit ,  SÁGHY, Katalin ,  SCHMIDT, Éva ,  FARKAS, Sándor ,  KOMLÓDI, Zsolt

IPC分类号： C07D239/48 ,  A61K31/506 ,  A61P25/00

CPC分类号： C07D239/48

摘要： The present invention relates to new dopamine D3 and D2 ligands of formula (I): wherein Rl, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes for preparing the same, to compositions containing the same and to their use in the treatment and/or prevention of conditions which requires modulation of dopamine receptors.