公开(公告)号：EP1618210B1

公开(公告)日：2010-09-01

申请号：EP04728336.1

申请日：2004-04-20

申请人： Roche Diagnostics GmbH ,  F. Hoffmann-La Roche AG

发明人： HIGUCHI, Russell, Gene ,  PELTZ, Gary, Allen ,  FIJAL, Bonnie ,  RO, Sunhee, Kwon ,  LI, Jia

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/156

摘要： Methods and reagents for determining sequence variants present at the FRZB locus, which facilitate identifying individuals at risk for obesity and/or osteoporosis, are provided. In particular, methods for detecting an individual's risk for obesity and/or osteoporosis by detecting at least one polymorphism (e.g., at least one single nucleotide polymorphism) in the FRZB gene in a nucleic acid sample from the individual are provided. Related kits, arrays and systems are also described.

公开(公告)号：EP1618210A1

公开(公告)日：2006-01-25

申请号：EP04728336.1

申请日：2004-04-20

申请人： Roche Diagnostics GmbH ,  F. HOFFMANN-LA ROCHE AG

发明人： HIGUCHI, Russell, Gene ,  PELTZ, Gary, Allen ,  FIJAL, Bonnie ,  RO, Sunhee, Kwon ,  LI, Jia

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/156

摘要： Methods and reagents for determining sequence variants present at the FRZB locus, which facilitate identifying individuals at risk for obesity and/or osteoporosis, are provided. In particular, methods for detecting an individual's risk for obesity and/or osteoporosis by detecting at least one polymorphism (e.g., at least one single nucleotide polymorphism) in the FRZB gene in a nucleic acid sample from the individual are provided. Related kits, arrays and systems are also described.