公开(公告)号：EP1448604A4

公开(公告)日：2007-05-23

申请号：EP01274717

申请日：2001-11-22

申请人： SAMSUNG FINE CHEMICALS CO LTD

发明人： CHO KYU-IL ,  BAEK HYON-HO ,  KIM JUNG HYUN ,  LEE JUN YOUNG ,  KIM IL HYUK ,  PARK JUNG HWAN

IPC分类号： C08B13/00 ,  A61K9/28 ,  B01D61/14 ,  B01F17/42 ,  B01F17/52 ,  B01F17/56 ,  B01J19/00 ,  B01J39/04 ,  C08B15/02 ,  C08J3/16 ,  C08L1/32

CPC分类号： C08J3/16 ,  A61K9/2866 ,  C08J2301/32 ,  C08L1/32

摘要： The present invention relates to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, and more particularly, to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, which is environment-friendly and advantageous in disintegration and dissolution when used as an enteric coating material, which is prepared by obtaining suitable hydroxypropyl methyl cellulose phthalate (HPMCP) particle through aqueous emulsification process and regulating content of remaining electrolyte through ion exchange process.