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公开(公告)号：EP2983743B1
公开(公告)日：2019-05-22
申请号：EP14718939.3
申请日：2014-04-08
申请人： SANOFI
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2.发明公开HAND-HELD DRUG INJECTION DEVICE AND DOSE SETTING LIMITER MECHANISM THEREFOR 审中-公开手持式药物注入器具剂量设定控制机制THEREFOR
公开(公告)号：EP2983742A1
公开(公告)日：2016-02-17
申请号：EP14717719.0
申请日：2014-04-08
申请人： SANOFI
CPC分类号： A61M5/31553 , A61M5/2033 , A61M5/31541 , A61M5/31558 , A61M5/31563 , A61M5/3157 , A61M5/31575 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2005/202 , A61M2005/2086 , A61M2005/3126 , A61M2005/314 , A61M2005/3143 , A61M2005/31508 , A61M2005/3152 , A61M2005/3154 , A61M2205/581
摘要： The present invention relates to a drive mechanism of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising: —a housing (20), —a piston rod (120) extending in an axial direction (1, 2) to operably engage with a piston (14) of a cartridge (12), —a drive sleeve (90) rotatably supported in the housing (20), at least partially enclosing the piston rod (120), the drive sleeve (90) is operably releasable from the piston rod (120) for setting of a dose and the drive sleeve (90) is operably engageable with the piston rod (120) for dispensing of the dose, —a dose limiting member (130) threadedly engaged with the drive sleeve (90), rotatably locked to the housing (20) and being displaceable in axial direction (1, 2) in response to a rotation of the drive sleeve (90) relative to the piston rod (120), —at least one stop member (124) provided on the piston rod (120) to engage with the dose limiting member (130) for impeding a further displacement of the drive sleeve (90) relative to the piston rod (120), when a maximum dose configuration has been reached.
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公开(公告)号：EP2983763B1
公开(公告)日：2017-05-24
申请号：EP14716553.4
申请日：2014-04-08
申请人： SANOFI
发明人： BAYER, Stefan , BERNING, Daniel , BLANK, Philippe , PELZER, Wolfgang , PFOSER, Michael , WILDEN, Björn
CPC分类号： A61M5/315 , A61M5/20 , A61M5/24 , A61M5/31501 , A61M5/31511 , A61M5/31525 , A61M5/3153 , A61M5/31533 , A61M5/31541 , A61M5/31543 , A61M5/31545 , A61M5/31553 , A61M5/31563 , A61M5/31565 , A61M5/31583 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicament, and to a respective drug delivery device, wherein the drive mechanism comprises: an elongated housing (30) extending in an axial direction (1, 2), a piston rod (80) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in axial distal direction (1), a drive sleeve (60) extending in axial direction (1, 2) and being rotatably supported in the housing (30), a dose setting member (40) rotatably supported on a side wall portion (31) of the housing (30) and being rotatable with respect to an axis (41) extending in radial direction (r), wherein the drive sleeve (60) is operably releasable from the piston rod (80) and rotatably engageable with the dose setting member (40) for setting of the dose.
摘要翻译： 本发明涉及一种用于分配一剂药物的药物输送装置的驱动机构以及一种相应的药物输送装置，其中该驱动机构包括：细长壳体（30），该细长壳体沿轴向方向（1， （1）上的活塞杆（16）;与所述活塞杆（14）的活塞（16）可操作地接合以沿着轴向远端方向（1）移动所述活塞（16）的活塞杆（80）;沿轴向方向 可旋转地支撑在所述壳体（30）的侧壁部分（31）上的剂量设定构件（40），所述剂量设定构件可相对于延伸的轴线（41）旋转， 在径向方向（r）上，其中所述驱动套筒（60）可从所述活塞杆（80）可操作地释放，并可与所述剂量设定构件（40）可旋转地接合以设定剂量。
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公开(公告)号：EP2983754A1
公开(公告)日：2016-02-17
申请号：EP14715907.3
申请日：2014-04-08
申请人： SANOFI
CPC分类号： A61M5/31583 , A61M5/20 , A61M5/31541 , A61M5/31553 , A61M5/3157 , A61M2005/3126 , A61M2005/3154 , A61M2205/581 , A61M2205/582
摘要： The present invention relates to a drive member of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising: a housing (30) extending in an axial direction (1, 2), a piston rod (90) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in an axial distal direction (1), a dose indicating mechanism (130) comprising a first spool (140; 240) and a second spool (142; 242) rotatably supported in the housing (30), wherein first and second spools (140, 142; 240, 242) are oriented substantially parallel to each other and substantially parallel to the piston rod (90), a dose indicating tape (146; 246) coiled onto at least the second spool (142; 242) and fixed with an end to an outer circumference of the first spool (140; 240).
摘要翻译： 本发明涉及用于分配一剂药物的药物输送装置的驱动构件，该机构包括：沿轴向（1,2）延伸的壳体（30），活塞杆（90）以可操作地 与药筒（14）的活塞（16）接合以沿轴向远端方向（1）移动活塞（16），剂量指示机构（130）包括第一卷轴（140; 240）和第二卷轴 其中第一和第二卷轴（140,142; 240,242）基本上彼此平行地定向并基本平行于所述活塞杆（90），剂量指示带（140,142; 240,242） 卷绕在至少第二卷轴（142; 242）上并且其一端固定到第一卷轴（140; 240）的外圆周上。
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公开(公告)号：EP2983739A1
公开(公告)日：2016-02-17
申请号：EP14716288.7
申请日：2014-04-08
申请人： SANOFI
摘要： A drive mechanism of a drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction, and a drive sleeve extending in the axial direction and being rotatable in a dose incrementing direction against the action of a spring enclosing at least an axial portion of the drive sleeve. The drive mechanism further includes a dose limiting member threadedly engaged with the drive sleeve, rotatably locked to the housing and at least partially extending radially between the drive sleeve and the spring, and at least one stop located on at least one of dose limiting member and drive sleeve for limiting an axial displacement of the dose limiting member relative to the drive sleeve.
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公开(公告)号：EP2983735B1
公开(公告)日：2020-12-09
申请号：EP14715611.1
申请日：2014-04-08
申请人： SANOFI
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公开(公告)号：EP2983751A1
公开(公告)日：2016-02-17
申请号：EP14715612.9
申请日：2014-04-08
申请人： SANOFI
发明人： BAYER, Stefan , BERNING, Daniel , BLANK, Philippe , PELZER, Wolfgang , PFOSER, Michael , WILDEN, Björn
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/31541 , A61M5/31548 , A61M5/31553 , A61M5/31563 , A61M5/31568 , A61M5/31585 , A61M5/31593 , A61M2205/581
摘要： A drug delivery device for dispensing a dose of a medicament includes an elongated housing extending in an axial direction, and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive sleeve extending in an axial direction and being rotatable against the action of a spring during a dose setting procedure and a dispensing sleeve rotatably engaged with the piston rod and being displaceable in an axial direction relative to the drive sleeve to engage with the drive sleeve in a torque transmissive way during a dose dispensing procedure.
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公开(公告)号：EP2983743A1
公开(公告)日：2016-02-17
申请号：EP14718939.3
申请日：2014-04-08
申请人： SANOFI
发明人： BAYER, Stefan , BERNING, Daniel , BLANK, Philippe , PELZER, Wolfgang , PFOSER, Michael , WILDEN, Björn
CPC分类号： A61M5/31541 , A61M5/20 , A61M5/31553 , A61M5/3157 , A61M5/31583 , A61M2005/3154 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism for a drug delivery device includes an elongated housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. A drive sleeve is rotatably supported in the housing, operably releasable from the piston rod for setting of a dose, and operably engageable with the piston rod for dispensing of the dose. A dose limiting member is engaged with the drive sleeve and engaged with the piston rod in such a way that it is displaced in axial direction relative to the drive sleeve when the drive sleeve rotates relative to the piston rod during a dose setting procedure. At least one stop is configured to engage with the dose limiting member for limiting the axial displacement of the dose limiting member during the dose setting procedure and to impede further displacement of the drive sleeve relative to the piston rod.
摘要翻译： 本发明涉及一种用于药物输送装置和相应药物输送装置的驱动机构，其中该驱动机构包括：沿轴向方向（1,2）延伸的细长壳体（20），活塞杆（70） ）与盒（14）的活塞（16）可操作地接合以沿轴向远侧方向（1）移动活塞（16），驱动套筒（50）可旋转地支撑在壳体（20）中并且可操作地 可从活塞杆（70）释放以用于设定剂量并且可与活塞杆（70）可操作地接合以分配剂量;剂量限制构件（60），其与驱动套筒（50）接合并且与剂量限制构件 活塞杆（70）以这种方式在驱动套筒（50）相对于活塞杆（70）相对于活塞杆（70）旋转期间在剂量设定期间相对于驱动套筒（50）沿轴向方向（1,2） 程序以及与剂量限制构件（60）接合以限制轴向位移的至少一个止动件（42,56; 78） 在所述剂量设定过程期间所述剂量限制构件（60）的所述第一部分和所述驱动套筒（50）相对于所述活塞杆（70）进一步移位。
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10.发明公开DRIVE MECHANISM OF A DRUG DELIVERY DEVICE 有权ANTRIEBSMECHANISMUSFÜREINE MEDIKAMENTENABGABEVORRICHTUNG
公开(公告)号：EP2983769A1
公开(公告)日：2016-02-17
申请号：EP14718364.4
申请日：2014-04-08
申请人： SANOFI
CPC分类号： A61M5/315 , A61M5/20 , A61M5/24 , A61M5/31511 , A61M5/31533 , A61M5/31541 , A61M5/31553 , A61M5/31583 , A61M5/31593 , A61M2005/3126
摘要： The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: -a housing (20), -a piston rod (120) to operably engage with a piston (14) of a cartridge (12) for displacing the piston (14) in a distal direction (1), -a dose indicating member (40) with a dose size information (48) thereon, connected to a spring element (100) and being rotatable in a dose incrementing direction (5) against the action of the spring element (100) for setting of a dose, -a drive wheel (130) operably engaged with the piston rod (120) for displacing the piston rod (120) in distal direction (1) for dose dispensing, -wherein the dose indicating member (40) is engageable with the drive wheel (130) during dose dispensing to transfer a driving force to the drive wheel (130) when driven by the relaxing spring element (100) in a dose decrementing direction (6).
摘要翻译： 本发明涉及一种用于设置和分配药物剂量的药物输送装置的驱动机构，该机构包括：一个壳体（20），一个可与活塞（14）可操作地接合的活塞杆（120） ），用于沿远端方向（1）移动所述活塞（14）， - 连接到弹簧元件（100）上的剂量指示构件（40），其上具有剂量尺寸信息（48），并且是一个 可旋转的剂量递增方向（5）抵抗弹簧元件（100）的作用，用于设定剂量， - 与活塞杆（120）可操作地接合的驱动轮（130），用于将活塞杆（120） 用于剂量分配的远侧方向（1），其中剂量指示构件（40）在剂量分配期间可与驱动轮（130）接合，以在由松弛弹簧元件驱动时将驱动力传递到驱动轮（130） 100）以剂量递减方向（6）。
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