专利检索 ap:("SANOFI") AND inv:"BONNEVAUX, Hélène" 第 1 页

1.

发明公开
ANTI-TUMORAL COMPOSITION COMPRISING A PI3KBETA-SELECTIVE INHIBITOR AND A PI3KALPHA-SELECTIVE INHIBITOR 审中-公开
标题翻译： WITH A PI3KBETA选择性抑制剂AND A PI3KALPHA选择性抑制剂抗肿瘤药物组合物

公开(公告)号：EP2981261A1

公开(公告)日：2016-02-10

申请号：EP14714736.7

申请日：2014-04-03

申请人： SANOFI

发明人： BONNEVAUX, Hélène , GARCIA-ECHEVERRIA, Carlos , VIRONE-ODDOS, Angela

IPC分类号： A61K31/4439 , A61K31/513 , A61K45/06 , A61P35/00

CPC分类号： A61K31/5377 , A61K31/4439 , A61K31/513 , A61K45/06 , A61K2300/00

摘要： The present invention concerns a combination of a PI3Kβ selective inhibitor with a PI3Kα selective inhibitor for use in the treatment of cancer.

2.

发明公开
ANTI-TUMORAL COMPOSITION COMPRISING A PI3KBETA INHIBITOR AND A RAF INHIBITOR, TO OVERCOME CANCER CELLS RESISTANCE 审中-公开
标题翻译：与β抑制剂PI3K和RAF抑制剂克服癌细胞抵抗抗肿瘤药物组合物

公开(公告)号：EP2968350A1

公开(公告)日：2016-01-20

申请号：EP14710274.3

申请日：2014-03-14

申请人： SANOFI

发明人： BONNEVAUX, Hélène , GARCIA-ECHEVERRIA, Carlos , VIRONE-ODDOS, Angela

IPC分类号： A61K31/538 , A61K31/437 , A61P35/00

CPC分类号： A61K31/5377 , A61K31/437 , A61K31/5375 , A61K45/06 , G01N33/5011 , G01N33/5017 , G01N33/57496 , A61K2300/00

摘要： The present invention concerns a combination of a ΡΙ3Κβ inhibitor with a RAF inhibitor for its use for the treatment of a patient resistant to at least one RAF inhibitor, a kit comprising the same, its pharmaceutical uses thereof and a method of monitoring the efficiency of said combination when administered to a patient.