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1.发明公开HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF 有权杂环化合物，它们的制备方法，含有这些化合物和它们的药物使用
公开(公告)号：EP2310372A2
公开(公告)日：2011-04-20
申请号：EP09776990.5
申请日：2009-07-07
申请人： Sanofi-Aventis
IPC分类号： C07D213/69 , C07D319/06 , C07D237/16 , C07D405/12 , A61K31/44 , A61K31/50 , A61K31/357 , A61P3/00 , A61K31/4433
CPC分类号： C07D213/69 , C07D237/16 , C07D319/06 , C07D405/12
摘要： Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, T and Y have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example for the treatment of the metabolic syndrome, insulin resistance, obesity and diabetes.
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2.发明公开PHENOTHIAZIN DERIVATE MIT DOPPELBINDUNG, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权吩噻嗪衍生物的双键，其制造方法相同，它们作为药物
公开(公告)号：EP2203448A1
公开(公告)日：2010-07-07
申请号：EP08785816.3
申请日：2008-09-04
申请人： Sanofi-Aventis
发明人： KEIL, Stefanie , DEFOSSA, Elisabeth , SCHMOLL, Dieter , DIETRICH, Axel , KUHLMANN, Johanna , ENGEL, Karl-Christian
IPC分类号： C07D417/12 , C07D513/04 , A61K31/5415 , A61P3/10
CPC分类号： C07D417/12 , C07D513/04
摘要： The invention relates to compounds of the formula (I), wherein the groups R1, R2, R3, R4, R5, R6, and R7, and A and B have the stated meanings, and the physiologically compatible salts thereof. The compounds are suitable, for example, as antidiabetics.
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3.发明公开CYCLOALKYL SUBSTITUIERTE 7-AMINO-4-CHINOLON-3-CARBONSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物，METHOD FOR它们的生产和它们作为药物
公开(公告)号：EP1713804A1
公开(公告)日：2006-10-25
申请号：EP05700960.7
申请日：2005-01-15
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , KLABUNDE, Thomas , SCHMOLL, Dieter , HERLING, Andreas , WENDT, Karl-Ulrich , RUF, Sven
IPC分类号： C07D471/04 , A61K31/4375 , A61P3/10
CPC分类号： C07D471/04
摘要： The invention relates to cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives as well as their physiologically compatible salts and physiologically functional derivatives. The invention concerns compounds of formula (I), wherein the radicals have the cited meanings, and the physiologically compatible salts thereof. The compounds are suited for use, e.g. as medicaments for preventing and treating type 2 diabetes.
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4.发明授权Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof 有权杂环化合物，它们的制备方法，含有这些化合物和它们的药物使用
公开(公告)号：EP2310372B1
公开(公告)日：2012-05-23
申请号：EP09776990.5
申请日：2009-07-07
申请人： SANOFI
IPC分类号： C07D213/69 , C07D319/06 , C07D237/16 , C07D405/12 , A61K31/44 , A61K31/50 , A61K31/357 , A61P3/00 , A61K31/4433
CPC分类号： C07D213/69 , C07D237/16 , C07D319/06 , C07D405/12
摘要： Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, T and Y have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example for the treatment of the metabolic syndrome, insulin resistance, obesity and diabetes.
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5.发明公开
公开(公告)号：EP2114937A1
公开(公告)日：2009-11-11
申请号：EP08706994.4
申请日：2008-01-11
申请人： Sanofi-Aventis
发明人： KEIL, Stefanie , DEFOSSA, Elisabeth , SCHOENAFINGER, Karl , SCHMOLL, Dieter , DIETRICH, Axel , KUHLMANN, Johanna , ENGEL, Karl-Christian
IPC分类号： C07D417/14 , A61K31/5415 , A61P3/10 , C07D417/12 , C07D513/04
CPC分类号： C07D417/12 , C07D417/14 , C07D513/04
摘要： The invention relates to compounds of the formula (I), wherein the radicals R1, R2, R3, R4, R5, R6 and R7 and A and B are defined as indicated, and also to the physiologically tolerable salts thereof. The compounds are suited, for example, as anti-diabetics.
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6.发明公开HETEROCYCLISCH SUBSTITUIERTE 7-AMINO-4-CHINOLON-3-CARBONSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权杂环取代的7-氨基-4-喹诺酮-3-羧酸衍生物，METHOD FOR它们的生产和它们作为药物
公开(公告)号：EP1720870A1
公开(公告)日：2006-11-15
申请号：EP05700959.9
申请日：2005-01-15
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , RUF, Sven , KLABUNDE, Thomas , SCHMOLL, Dieter , HERLING, Andreas , WENDT, Karl-Ulrich
IPC分类号： C07D471/04 , C07D401/12 , A61K31/4375 , A61K31/47 , A61P3/10
CPC分类号： C07D417/12 , C07D215/56 , C07D401/12 , C07D471/04
摘要： The invention relates to heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives as well as their physiologically compatible salts and physiologically functional derivatives. The invention concerns compounds of formula (I), wherein the radicals have the cited meanings, and the physiologically compatible salts thereof. The compounds are suited for use, e.g. as medicaments for preventing and treating type 2 diabetes.
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7.发明授权CYCLOALKYL SUBSTITUIERTE 7-AMINO-4-CHINOLON-3-CARBONSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物，METHOD FOR它们的生产和它们作为药物
公开(公告)号：EP1713804B1
公开(公告)日：2008-03-19
申请号：EP05700960.7
申请日：2005-01-15
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , KLABUNDE, Thomas , SCHMOLL, Dieter , HERLING, Andreas , WENDT, Karl-Ulrich , RUF, Sven
IPC分类号： C07D471/04 , A61K31/4375 , A61P3/10
CPC分类号： C07D471/04
摘要： The invention relates to cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives as well as their physiologically compatible salts and physiologically functional derivatives. The invention concerns compounds of formula (I), wherein the radicals have the cited meanings, and the physiologically compatible salts thereof. The compounds are suited for use, e.g. as medicaments for preventing and treating type 2 diabetes.
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8.发明授权HETEROCYCLISCH SUBSTITUIERTE 7-AMINO-4-CHINOLON-3-CARBONSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权杂环取代的7-氨基-4-喹诺酮-3-羧酸衍生物，METHOD FOR它们的生产和它们作为药物
公开(公告)号：EP1720870B1
公开(公告)日：2007-08-22
申请号：EP05700959.9
申请日：2005-01-15
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , RUF, Sven , KLABUNDE, Thomas , SCHMOLL, Dieter , HERLING, Andreas , WENDT, Karl-Ulrich
IPC分类号： C07D471/04 , C07D401/12 , A61K31/4375 , A61K31/47 , A61P3/10
CPC分类号： C07D417/12 , C07D215/56 , C07D401/12 , C07D471/04
摘要： The invention relates to heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives as well as their physiologically compatible salts and physiologically functional derivatives. The invention concerns compounds of formula (I), wherein the radicals have the cited meanings, and the physiologically compatible salts thereof. The compounds are suited for use, e.g. as medicaments for preventing and treating type 2 diabetes.
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9.发明公开7-PHENYLAMINO-4-CHINOLON-3-CARBONSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权7-苯基氨基-4-喹诺酮-3-羧酸衍生物，METHOD FOR它们的生产和它们作为药物
公开(公告)号：EP1713803A1
公开(公告)日：2006-10-25
申请号：EP05700953.2
申请日：2005-01-15
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , RUF, Sven , KLABUNDE, Thomas , SCHMOLL, Dieter , HERLING, Andreas , WENDT, Karl-Ulrich
IPC分类号： C07D471/04 , A61K31/4375 , A61P3/10 , C07D215/54 , C07F9/00 , C07D401/06
CPC分类号： C07F9/60 , C07D215/54 , C07D215/56 , C07D401/04 , C07D401/06 , C07D471/04
摘要： The invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, the physiologically-acceptable salts and physiologically-functional derivatives thereof, also compounds of formula (I), where the groups have the given meanings and the physiologically-acceptable salts thereof. Said compound are suitable for use, for example, as medicaments for the prevention and treatment of type 2 diabetes.
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10.发明授权
公开(公告)号：EP2114937B1
公开(公告)日：2011-06-29
申请号：EP08706994.4
申请日：2008-01-11
申请人： Sanofi-Aventis
发明人： KEIL, Stefanie , DEFOSSA, Elisabeth , SCHOENAFINGER, Karl , SCHMOLL, Dieter , DIETRICH, Axel , KUHLMANN, Johanna , ENGEL, Karl-Christian
IPC分类号： C07D417/14 , A61K31/5415 , A61P3/10 , C07D417/12 , C07D513/04
CPC分类号： C07D417/12 , C07D417/14 , C07D513/04
摘要： The invention relates to compounds of the formula (I), wherein the radicals R1, R2, R3, R4, R5, R6 and R7 and A and B are defined as indicated, and also to the physiologically tolerable salts thereof. The compounds are suited, for example, as anti-diabetics.
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