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1.发明授权
公开(公告)号：EP1194131B1
公开(公告)日：2004-09-01
申请号：EP00949361.0
申请日：2000-06-27
申请人： SANOFI-SYNTHELABO
IPC分类号： A61K9/50
CPC分类号： A61K9/5078 , A61K9/5015 , A61K9/5026
摘要： The present invention relates to delayed release coated cores comprising an active substance in their core and a polymer coating comprising at least one or more ammonio methacrylate copolymer, characterised in that the core comprises at least a surfactant; to monolithic or multiparticulate pharmaceutical dosage forms comprising such delayed release coated cores and to their method of manufacture.
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公开(公告)号：EP1121099B1
公开(公告)日：2004-04-21
申请号：EP99947537.9
申请日：1999-10-12
申请人： SANOFI-SYNTHELABO
发明人： ALAUX, Gérard , ANDRE, Frédéric , CUINE, Alain , LEWIS, Gareth
CPC分类号： A61K31/166 , A61K9/0007 , A61K9/209 , A61K31/40
摘要： The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterised in that it comprises two or three layers and contains: (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.
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3.发明公开TIMED DUAL RELEASE DOSAGE FORMS COMPRISING A SHORT ACTING HYPNOTIC OR A SALT THEREOF 有权TIMED RELEASING剂型包含其短效催眠或盐
公开(公告)号：EP1194132A2
公开(公告)日：2002-04-10
申请号：EP00954518.7
申请日：2000-06-27
申请人： SANOFI-SYNTHELABO
发明人： ALAUX, Gérard , ANDRE, Frédéric , DUCASSOU, Jean , LEWIS, Gareth
CPC分类号： A61K31/437 , A61K9/5078 , A61K9/5084
摘要： The present invention relates to timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period, according to a profile of dissolution characterised in that it comprises two release pulses, the first being immediate (lasting up to 30 minutes) and the second being delayed by a fixed time (this fixed time being between 50 and 200 minutes).
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4.发明授权TIMED DUAL RELEASE DOSAGE FORMS COMPRISING A SHORT ACTING HYPNOTIC OR A SALT THEREOF 有权TIMED RELEASING剂型包含其短效催眠或盐
公开(公告)号：EP1194132B1
公开(公告)日：2004-06-16
申请号：EP00954518.7
申请日：2000-06-27
申请人： SANOFI-SYNTHELABO
发明人： ALAUX, Gérard , ANDRE, Frédéric , DUCASSOU, Jean , LEWIS, Gareth
CPC分类号： A61K31/437 , A61K9/5078 , A61K9/5084
摘要： The present invention relates to timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period, according to a profile of dissolution characterised in that it comprises two release pulses, the first being immediate (lasting up to 30 minutes) and the second being delayed by a fixed time (this fixed time being between 50 and 200 minutes).
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5.发明公开
公开(公告)号：EP1194131A1
公开(公告)日：2002-04-10
申请号：EP00949361.0
申请日：2000-06-27
申请人： SANOFI-SYNTHELABO
IPC分类号： A61K9/50
CPC分类号： A61K9/5078 , A61K9/5015 , A61K9/5026
摘要： The present invention relates to delayed release coated cores comprising an active substance in their core and a polymer coating comprising at least one or more ammonio methacrylate copolymer, characterised in that the core comprises at least a surfactant; to monolithic or multiparticulate pharmaceutical dosage forms comprising such delayed release coated cores and to their method of manufacture.
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公开(公告)号：EP1121099A1
公开(公告)日：2001-08-08
申请号：EP99947537.9
申请日：1999-10-12
申请人： SANOFI-SYNTHELABO
发明人： ALAUX, Gérard , ANDRE, Frédéric , CUINE, Alain , LEWIS, Gareth
CPC分类号： A61K31/166 , A61K9/0007 , A61K9/209 , A61K31/40
摘要： The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterised in that it comprises two or three layers and contains: (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.
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