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1.Process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions 失效
标题翻译: 制备哌啶二酮二缩水甘油醚(A,D)环烯酸和其衍生物的方法,通过这些方法获得的化合物和这些化合物用于制备有用的药物组合物公开(公告)号:EP0208855B1
公开(公告)日:1991-03-06
申请号:EP86106257.8
申请日:1986-05-07
申请人: SCHERING CORPORATION
发明人: Schumacher, Doris Pickel , Villani, Frank J. , Wong, Jesse Kwok-Keung , Murphy, Bruce Lee , Clark, Jon Edward
IPC分类号: C07D401/04 , C07D221/16 , C07D213/81 , A61K31/435
CPC分类号: C07D213/81 , C07D221/16 , C07D401/04
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2.Process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions 失效
标题翻译: 一种用于制备哌啶基二氢二苯并(A,D)和它们的zykloheptenen偶氮衍生物和化合物的方法,由此制备其用于制备药物的用途。公开(公告)号:EP0208855A1
公开(公告)日:1987-01-21
申请号:EP86106257.8
申请日:1986-05-07
申请人: SCHERING CORPORATION
发明人: Schumacher, Doris Pickel , Villani, Frank J. , Wong, Jesse Kwok-Keung , Murphy, Bruce Lee , Clark, Jon Edward
IPC分类号: C07D401/04 , C07D221/16 , C07D213/81 , A61K31/435
CPC分类号: C07D213/81 , C07D221/16 , C07D401/04
摘要: Disclosed is an improved process for preparing unsubstituted or substituted dihydro-dibenzo[a,d]cycloheptenes, azaderivatives thereof and the pharmaceutically acceptable salts of such compounds. A narrow group of compounds which possess antihistaminic properties with substantially no sedative properties and which are obtainable by the claimed process is also claimed.
摘要翻译: 公开的是用于制备unsubstituiertem或substituiertem二氢二苯并[a,D] cycloheptenes,其azaderivatives和药学上可接受的测试化合物的盐的改进方法。 其与基本上没有镇静特性具有抗组胺性质且化合物的窄组是可获得的通过该方法其特征在于,如此要求保护的。
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