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1.发明公开PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS 有权PYRAZOLOPYRIMIDINDERIVATE作为抑制剂细胞周期蛋白依赖性激酶
公开(公告)号：EP1720882A2
公开(公告)日：2006-11-15
申请号：EP05722809.0
申请日：2005-02-08
发明人： GUZI, Timothy J. , PARUCH, Kamil , DWYER, Michael P. , DOLL, Ronald J. , GIRIJAVALLABHAN, Viyyoor Moopil , MALLAMS, Alan , ALVAREZ, Carmen S. , KEERTIKAR, Kartik M. , RIVERA, Jocelyn , CHAN, Tin-Yau , MADISON, Vincent , FISCHMANN, Thierry O. , DILLARD, Lawrence W. , TRAN, Vinh D. , HE, Zhen Min , JAMES, Ray Anthony , PARK, Haengsoon , PARADKAR, Vidyadhar M. , HOBBS, Douglas Walsh
IPC分类号： C07D487/04 , A61K31/495 , A61P35/00
CPC分类号： C07D487/04 , A61K31/495
摘要： In its many embodiments, the present invention provides pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
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2.发明授权PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS 有权PYRAZOLOPYRIMIDINDERIVATE作为抑制剂细胞周期蛋白依赖性激酶
公开(公告)号：EP1720882B1
公开(公告)日：2011-01-05
申请号：EP05722809.0
申请日：2005-02-08
发明人： GUZI, Timothy J. , PARUCH, Kamil , DWYER, Michael P. , DOLL, Ronald J. , GIRIJAVALLABHAN, Viyyoor Moopil , MALLAMS, Alan , ALVAREZ, Carmen S. , KEERTIKAR, Kartik M. , RIVERA, Jocelyn , CHAN, Tin-Yau , MADISON, Vincent , FISCHMANN, Thierry O. , DILLARD, Lawrence W. , TRAN, Vinh D. , HE, Zhen Min , JAMES, Ray Anthony , PARK, Haengsoon , PARADKAR, Vidyadhar M. , HOBBS, Douglas Walsh
IPC分类号： C07D487/04 , A61K31/495 , A61P35/00
CPC分类号： C07D487/04 , A61K31/495
摘要： In its many embodiments, the present invention provides pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
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