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1.发明公开3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands 有权3,4-二取代的环丁烯-1,2-二酮作为CXC趋化因子受体配体
公开(公告)号：EP1818325A3
公开(公告)日：2008-02-13
申请号：EP07010711.5
申请日：2002-04-15
发明人： Taveras, Arthur G. , Aki, Cynthia J. , Bond, Richard W. , Chao, Jianping , Dwyer, Michael , Ferreira, Johan A. , Chao, Jianhua , Yu, Younong , Baldwin, John J. , Kaiser, Bernd , Li, Ge , Merritt, Robert J. , Nelson, Kingsley H. , Rokosz, Laura L.
IPC分类号： C07C237/30 , C07C255/59 , C07C225/20 , C07D213/74 , C07D307/52 , C07D333/36 , C07D249/18 , C07D231/38 , C07D207/36
CPC分类号： C07D231/38 , C07C225/20 , C07C237/30 , C07C255/59 , C07C2601/04 , C07D213/74 , C07D307/52 , C07D333/36
摘要： There are disclosed compounds of the formula
or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.-
2.发明公开3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands 有权3,4-DI取代物环丁烷-1,2-二酮αCXC-Chemokin-Rezeptorliganden
公开(公告)号：EP1818325A2
公开(公告)日：2007-08-15
申请号：EP07010711.5
申请日：2002-04-15
发明人： Taveras, Arthur G. , Aki, Cynthia J. , Bond, Richard W. , Chao, Jianping , Dwyer, Michael , Ferreira, Johan A. , Chao, Jianhua , Yu, Younong , Baldwin, John J. , Kaiser, Bernd , Li, Ge , Merritt, Robert J. , Nelson, Kingsley H. , Rokosz, Laura L.
IPC分类号： C07C237/30 , C07C255/59 , C07C225/20 , C07D213/74 , C07D307/52 , C07D333/36
CPC分类号： C07D231/38 , C07C225/20 , C07C237/30 , C07C255/59 , C07C2601/04 , C07D213/74 , C07D307/52 , C07D333/36
摘要： There are disclosed compounds of the formula
or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.摘要翻译： 公开了可用于治疗趋化因子介导的疾病如急性和慢性炎症性疾病和癌症的具有下式的化合物或其药学上可接受的盐或溶剂合物。
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3.发明授权3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands 有权3,4-二取代的环丁烯-1,2-二酮作为CXC趋化因子受体配体
公开(公告)号：EP1818325B1
公开(公告)日：2010-02-24
申请号：EP07010711.5
申请日：2002-04-15
发明人： Taveras, Arthur G. , Aki, Cynthia J. , Bond, Richard W. , Chao, Jianping , Dwyer, Michael , Ferreira, Johan A. , Chao, Jianhua , Yu, Younong , Baldwin, John J. , Kaiser, Bernd , Li, Ge , Merritt, Robert J. , Nelson, Kingsley H. , Rokosz, Laura L.
IPC分类号： C07C237/30 , C07C255/59 , C07C225/20 , C07D213/74 , C07D307/52 , C07D333/36 , C07D249/18 , C07D231/38 , C07D207/36
CPC分类号： C07D231/38 , C07C225/20 , C07C237/30 , C07C255/59 , C07C2601/04 , C07D213/74 , C07D307/52 , C07D333/36
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