公开(公告)号：EP0210189B1

公开(公告)日：1994-12-07

申请号：EP86900477.0

申请日：1985-12-10

申请人： SCIOS NOVA INC.

发明人： SCHILLING, James, W., Jr. ,  WHITE, Robert, T. ,  CORDELL, Barbara ,  BENSON, Bradley, J.

IPC分类号： C07K7/10 ,  A61K37/02 ,  C12N15/00

CPC分类号： C07K14/785 ,  A61K38/00 ,  Y10S930/30

摘要： Complete coding sequences and amino acid sequences for both canine and human 32K alveolar surfactant proteins (ASP); clones for the 10K protein have also been obtained. Methods and vectors for obtaining these proteins in recombinant form. The availability of large amounts of these proteins through recombinant techniques permits the use of ASP in suitable pharmaceutical compositions in the treatment of respiratory deficiency syndromes.