专利检索 ap:("SCRIPPS RESEARCH INST") AND inv:"SMIDER VAUGHN V" 第 1 页

1.

发明公开
BREAKING IMMUNOLOGICAL TOLERANCE WITH A GENETICALLY ENCODED UNNATURAL AMINO ACID 审中-公开
标题翻译：免疫耐受性与遗传编码的非天然氨基酸的中断

公开(公告)号：EP2249865A4

公开(公告)日：2012-04-04

申请号：EP09708010

申请日：2009-02-07

申请人： SCRIPPS RESEARCH INST

发明人： GRUNEWALD JAN , TSAO MENG-LIN , PERERA ROSHAN , LERNER RICHARD A , SMIDER VAUGHN V , SCHULTZ PETER G

IPC分类号： A61K39/395 , A61K31/198 , A61K39/00 , A61P25/28 , A61P35/00 , A61P37/04 , C12P21/02 , C12Q1/68

CPC分类号： C07K16/241 , A61K31/19 , A61K39/0008 , C07K16/44

摘要： The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety.