公开(公告)号：EP1632476A4

公开(公告)日：2007-05-16

申请号：EP04745313

申请日：2004-05-19

申请人： SEIKAGAKU KOGYO CO LTD

发明人： SUZUKI KIYOSHI ,  IIDA MASAMI ,  KANEDA YUJI ,  KUNII NAOKO ,  SAWA MIWA

IPC分类号： C07C215/44 ,  A61K31/133 ,  A61K31/155 ,  A61P3/06 ,  A61P3/10 ,  C07C213/08 ,  C07C249/02 ,  C07C251/04 ,  C07C277/08 ,  C07C279/16

CPC分类号： C07C215/44

摘要： An acid addition salt of a carbasugar amine derivative represented by the following general formula (1): wherein R and R each independently represents hydrogen or an alkyl, alkenyl, alkynyl, acyl, aryl, or aralkyl group optionally having one or more substituents represented by the following (I) or (II), or R and R in combination represent a substituent represented by the following (III): (wherein R to R each independently represents alkyl, alkenyl, alkynyl, acyl, aryl, or aralkyl), provided that not both of R and R are hydrogen; R , R , and R each independently represents hydroxy or substituted hydroxy; and R and R each independently represents hydrogen, hydroxy, or substituted hydroxy, provided that when one of R and R is hydrogen, then the other is hydroxy or substituted hydroxy.

摘要翻译： 由下述通式（1）表示的卡巴糖胺衍生物的酸加成盐：其中R 1和R 2各自独立地表示氢或任选地具有取代基的烷基，烯基，炔基，酰基，芳基或芳烷基 （I）或（II）表示的一个或多个取代基，或者R 1和R 2一起表示由以下（III）表示的取代基：（其中R 8至R 12表示） 各自独立地表示烷基，烯基，炔基，酰基，芳基或芳烷基），条件是不是R 1和R 2都是氢; R 3，R 4和R 7各自独立地表示羟基或取代的羟基; 并且R 5和R 6各自独立地表示氢，羟基或取代的羟基，条件是当R 5和R 6中的一个是氢时，则另一个是羟基或取代的羟基。