公开(公告)号：EP2723873B2

公开(公告)日：2020-01-15

申请号：EP12728499.0

申请日：2012-06-15

申请人： SESVanderHave N.V.

发明人： KLEIN, Elodie ,  GRAFF, Véronique ,  GILMER, David ,  BRAULT, Véronique ,  WEYENS, Guy ,  LEFEBVRE, Marc

IPC分类号： C12N15/82

公开(公告)号：EP2723873B1

公开(公告)日：2017-08-09

申请号：EP12728499.0

申请日：2012-06-15

申请人： SESVanderHave N.V.

发明人： KLEIN, Elodie ,  GRAFF, Véronique ,  GILMER, David ,  BRAULT, Véronique ,  WEYENS, Guy ,  LEFEBVRE, Marc

IPC分类号： C12N15/82

摘要： The present invention is related to a recombinant BMYV P0 viral nucleotide sequence when transcribed in a cell is capable of forming a double stranded self-complementary RNA sequence.

摘要翻译： 本发明涉及当在细胞中转录时能够形成双链自身互补RNA序列的重组BMYV P0病毒核苷酸序列。

公开(公告)号：EP2013231B1

公开(公告)日：2012-10-03

申请号：EP07728713.4

申请日：2007-05-02

申请人： SESVanderHave N.V.

发明人： LAUBER, Emmanuelle ,  GUILLEY, Hubert ,  RICHARDS, Ken ,  JONARD, Gerard ,  KLEIN, Elodie ,  GILMER, David

IPC分类号： C12N15/82

CPC分类号： C12N15/8283

公开(公告)号：EP2723873A1

公开(公告)日：2014-04-30

申请号：EP12728499.0

申请日：2012-06-15

申请人： SESVanderHave N.V.

发明人： KLEIN, Elodie ,  GRAFF, Véronique ,  GILMER, David ,  BRAULT, Véronique ,  WEYENS, Guy ,  LEFEBVRE, Marc

IPC分类号： C12N15/82

摘要： The present invention is related to a recombinant BMYV P0 viral nucleotide sequence when transcribed in a cell is capable of forming a double stranded self-complementary RNA sequence.

摘要翻译： 当在细胞中转录能够形成双链自身互补RNA序列时，本发明涉及重组BMYV P0病毒核苷酸序列。

公开(公告)号：EP2013231A2

公开(公告)日：2009-01-14

申请号：EP07728713.4

申请日：2007-05-02

申请人： Sesvanderhave N.V.

发明人： LAUBER, Emmanuelle ,  GUILLEY, Hubert ,  RICHARDS, Ken ,  JONARD, Gerard ,  KLEIN, Elodie ,  GILMER, David

IPC分类号： C07K14/08

CPC分类号： C12N15/8283

摘要： The invention relates to genetically modified TGB- 3 viral sequences suitable to induce gene silencing. In particular, hairpin constructs based on such sequences proved highly efficient to induce a PTGS mechanism and degradation of the whole of RNA2 thereby. When plants are transformed accordingly, the spread of the virus in the plant is significantly reduced or blocked. The invention relates of the hairpin constructs, their use and to plants, plant cells and plant tissues harboring these constructs.