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1.发明公开ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF 有权α-氨基的N-取代酰胺，药物组合物，其这包含，及其用途
公开(公告)号：EP2233467A1
公开(公告)日：2010-09-29
申请号：EP08858616.9
申请日：2008-12-11
发明人： NAN, Fajun , LI, Jia , DING, Jian , LIU, Gang , XIE, Chuanming , MIAO, Zehong , TAI, Wanyi
IPC分类号： C07C237/16 , C07C233/05 , C07C233/09 , C07C233/18 , C07C233/20 , A61K31/16 , A61P35/00
CPC分类号： C07C237/22 , C07C247/12 , C07C271/22 , C07C323/60 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2603/74 , C07D209/14 , C07D209/20 , C07D233/54 , C07D307/24 , C07D307/94
摘要： The present invention relates to filed of pharmaceutical chemistry. Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.
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2.发明授权ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF 有权α-氨基的N-取代酰胺，药物组合物，其这包含，及其用途
公开(公告)号：EP2233467B1
公开(公告)日：2012-09-19
申请号：EP08858616.9
申请日：2008-12-11
发明人： NAN, Fajun , LI, Jia , DING, Jian , LIU, Gang , XIE, Chuanming , MIAO, Zehong , TAI, Wanyi
IPC分类号： C07C237/16 , C07C233/05 , C07C233/09 , C07C233/18 , C07C233/20 , A61K31/16 , A61P35/00
CPC分类号： C07C237/22 , C07C247/12 , C07C271/22 , C07C323/60 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2603/74 , C07D209/14 , C07D209/20 , C07D233/54 , C07D307/24 , C07D307/94
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