公开(公告)号：EP3189841A4

公开(公告)日：2018-04-18

申请号：EP15838647

申请日：2015-09-03

申请人： SHIONOGI & CO

发明人： KAWASAKI HIDENORI ,  KOJIMA NATSUKO ,  FUJIHIRA ATSUSHI ,  TAKAHASHI KANAKO ,  MATSUBARA FUMIHIKO ,  MATSUOKA NAO

IPC分类号： A61K31/546 ,  A61K9/00 ,  A61K9/19 ,  A61K47/02 ,  A61K47/12 ,  A61K47/20 ,  A61K47/26 ,  A61P31/04

CPC分类号： A61K31/546 ,  A61K9/0019 ,  A61K9/19 ,  A61K47/02 ,  A61K47/12 ,  A61K47/20 ,  A61K47/26

摘要： The present invention relates to a stable pharmaceutical composition comprising a compound represented by formula (I), its pharmaceutically acceptable salt or a solvate thereof. The stable pharmaceutical composition can be prepared by comprising 1) a compound represented by formula (I), its pharmaceutically acceptable salt, or a solvate thereof, 2) one or more selected from the group consisting of alkali metal chlorides, alkaline earth metal chlorides, transition metal chlorides and magnesium chloride; and 3) sugar and/or a sugar alcohol.