公开(公告)号：EP1392338B1

公开(公告)日：2008-05-07

申请号：EP02771574.7

申请日：2002-01-04

申请人： SK CHEMICALS CO., LTD.

发明人： HAN, Chang-Kyun ,  KWAK, Wie-Jong ,  JOUNG, Ki Won ,  YOO, Hun Seung, 101-603 TaejinAhreum Apt. ,  KUM, Do Seung ,  CHO, Yong-Baik, 101-1105 Ggoomaeul Apt. ,  RYU, Keun Ho, A-201 Hwapyung Villa ,  RHEE, Hae In ,  KIM, Taek Su ,  JUNG, In Ho ,  LEE, So Yoon ,  YI, Jung Bum ,  KIM, Joo Hyon, 45/502 JamsilSiyoung Apt. ,  UM, Key An

IPC分类号： A61K36/428 ,  A61K36/536 ,  A61K36/716 ,  A61P19/00

CPC分类号： A61K36/536 ,  A61K36/428 ,  A61K36/716 ,  A61K2300/00

摘要： The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.