公开(公告)号：EP0555324B1

公开(公告)日：1997-03-12

申请号：EP91919728.5

申请日：1991-10-31

申请人： SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES

发明人： LE GOFF, Jean-Pierre ,  GAVACH, Claude, CNRS, Lab. de Physico-Chimie des ,  SANDEAUX, Roger, CNRS, Lab. de Physico-Chimie des ,  SANDEAUX, Jacqueline, CNRS, Lab. de Physico-Chimie

IPC分类号： C07C227/40 ,  C07C227/28

CPC分类号： C07C227/28 ,  C07C227/40

摘要： A method of separating the acidic, basic and amphoteric components of an aqueous mixture of amino acids, which comprises introducing the mixture into a first electrodialyser chamber bounded by a cation exchange membrane and an anion exchange membrane, applying an electric potential across the chamber to cause the basic components to pass through the cation exchange membrane into a second electrodialyser chamber bounded by a further anion exchange membrane, and the acidic components to pass through the anion exchange membrane into a third electrodialyser chamber bounded by a further cationic exchange membrane, and maintaining the electric potential to permit the basic components and acidic components to accumulate in the second and third chambers respectively, thereby leaving the amphoteric components in the first chamber.